ArticleJournal of nanobiotechnology2021
A dual-quenched ECL immunosensor for ultrasensitive detection of retinol binding protein 4 based on luminol@AuPt/ZIF-67 and MnO
Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 36 citations in OpenAlex.
- A quenched electrochemiluminescence immunosensor based on luminol-Au NPs/Co-Fe-MOF and CuO@UiO-66-NHMikrochimica acta · 2026Article
- Detection of profenofos based on an aptamer-regulated luminol-Au@CeOMikrochimica acta · 2026Article
- Au-g-CJournal of nanobiotechnology · 2025Article
- Amplification-Free Electrochemiluminescent Biosensor for Ultrasensitive Detection ofCyborg and bionic systems (Washington, D.C.) · 2025Article
- Target response controlled enzyme activity switch for multimodal biosensing detection.Journal of nanobiotechnology · 2023Article
- Electrochemiluminescence Systems for the Detection of Biomarkers: Strategical and Technological Advances.Biosensors · 2022Review
- Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundRetinol binding protein 4 (RBP4) has been regarded as an important serological biomarker for type 2 diabetes mellitus (T2DM). Hence, the construction of a highly sensitive detection method for RBP4 is the key to early prevention and multidisciplinary intervention of T2DM. In this work, a dual-quenched electrochemiluminescence (ECL) immunosensor has been fabricated for ultrasensitive detection of RBP4 by combining zeolitic imidazolate framework-67/AuPt-supported luminol (luminol@AuPt/ZIF-67) with MnO
resultsAuPt/ZIF-67 hybrids with high-efficiency peroxidase-like activity could provide multipoint binding sites for luminol and antibodies and significantly boost the amplified initial signal of the ECL immunosensor. Upon glutathione/H
conclusionsBenefiting from the above-mentioned properties, the designed immunoassay sensitivity exhibited excellent sensitivity and relative stability for RBP4 detection range from 0.0001 to 100 ng mL
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Registered trials
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