Evidence map›Paper›PMID 34496846›Full record

ArticleBMC veterinary research2021

Molecular detection and genetic characterization of Wenzhou virus in rodents in Guangzhou, China.

Nina Wang, Lichao Yang, Guohui Li, Xu Zhang, Jianwei Shao, Jun Ma, Shouyi Chen, Quan Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nina WangSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China.
Lichao YangSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China.
Guohui LiSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China.
Xu ZhangSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China.
Jianwei ShaoSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China.
Jun MaSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China.
Shouyi ChenGuangzhou Center for Disease Control and Prevention, 510440, Guangzhou, Guangdong Province, China. shouyi_chen@163.com.
Quan LiuSchool of Life Sciences and Engineering, Foshan University, 440605, Foshan, Guangdong Province, China. liuquan1973@hotmail.com.
Foshan University · CNGuangzhou Center for Disease Control and Prevention · CN

Funding

key laboratory for preventive research of emerging animal diseases in foshan university KLPREAD201801-13pearl river talent plan in guangdong province of china 2019CX01N111science and technology project of guangzhou, guangdong province of china 202103000008
6 · The paper itself

Abstract

backgroundWenzhou virus (WENV), a newly discovered mammarenavirus in rodents, is associated with fever and respiratory symptoms in humans. This study was aimed to detect and characterize the emerging virus in rodents in Guangzhou, China.

resultsA total of 100 small mammals, including 70 Rattus norvegicus, 22 Suncus murinus, 4 Bandicota indica, 3 Rattus flavipectus, and 1 Rattus losea, were captured in Guangzhou, and their brain tissues were collected and pooled for metagenomic analysis, which generated several contigs targeting the genome of WENV. Two R. norvegicus (2.9%) were further confirmed to be infected with WENV by RT-PCR. The complete genome (RnGZ37-2018 and RnGZ40-2018) shared 85.1-88.9% nt and 83.2-96.3% aa sequence identities to the Cambodian strains that have been shown to be associated with human disease. Phylogenetic analysis showed that all identified WENV could be grouped into four different lineages, and the two Guangzhou strains formed an independent clade. We also analyzed the potential recombinant events occurring in WENV strains.

conclusionsOur study showed a high genetic diversity of WENV strains in China, emphasizing the relevance of surveillance of this emerging mammarenavirus in both natural reservoirs and humans.

Indexed as

Genetic VariationPhylogenyAnimalsArenaviridaeBrainChinaHumansMetagenomicsRecombination, GeneticRodentiaChinaGuangzhoumammarenavirusphylogenetic analysisrodentsWenzhou virus

Identifiers

PMID34496846
PMCPMC8424800
OpenAlexW3197555594

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.