ReviewBMC pediatrics2021
Vitamin D prophylaxis in infancy.
Review in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effects of Maternal Vitamin D Supplementation on Childhood Health.Endocrine reviews · 2026Pooled it
- Effects of Maternal Vitamin D Supplementation on Childhood Health.Endocrine reviews · 2025Pooled it
- Article
- Lower Adherence to Vitamin D Prophylaxis in Families With Multiple Children.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Review
- Serum 25 hydroxyvitamin D was positively associated with hemoglobin and other anemia parameters in children: a cross-sectional study.Nutrition & metabolism · 2025Article
- Critical vitamin D and iron intakes in infants aged 6-11 months: results from the nationwide German KiESEL study.Frontiers in nutrition · 2025Article
- The Importance of Determining the Level of Bone Metabolism Markers and Vitamin D in the First Year of Life in the Kazakh Population.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Mini-Review on Vitamin D in Pediatric Population and its Role in Respiratory and Atopic Disorders.Mini reviews in medicinal chemistry · 2024Review
- Vitamin D status, vitamin D receptor, CYP2R1, and CYP24A1 profiles in children.Frontiers in nutrition · 2024Article
- Review
- Risk Assessment of Micronutrients Deficiency in Vegetarian or Vegan Children: Not So Obvious.Nutrients · 2023Review
- Dietary Supplements among Children Ages 0-3 Years in Poland-Are They Necessary?Foods (Basel, Switzerland) · 2022Article
- Vitamin D food fortification in European countries: the underused potential to prevent cancer deaths.European journal of epidemiology · 2022Review
- Exclusive Breastfeeding and Vitamin D Supplementation: A Positive Synergistic Effect on Prevention of Childhood Infections?International journal of environmental research and public health · 2022Review
- Primary health care for children - evidence for prevention.BMC pediatrics · 2021Article
- Prevention and Treatment of Vitamin D Deficiency in India: An Expert Group Consensus.Indian journal of endocrinology and metabolismReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We looked at existing recommendations and supporting evidence on the effectiveness of vitamin D supplementation in infancy for reducing vitamin D deficiency and for preventing rickets and infections. We also looked at optimal dose of vitamin D and the age until which vitamin D supplementation is beneficial.We conducted a literature search up to the 17th of July 2019 by using key terms and manual search in selected sources. We summarized the recommendations and the strength of the recommendation when and as reported by the authors. We summarized the main findings of systematic reviews with the certainty of the evidence as reported.A daily dose of 400 international units of vitamin D in infants has shown to be effective for improving bone health and preventing rickets. Evidence is more robust in groups of infants and children at risk. Vitamin D supplementation is well tolerated, and not associated with toxicity. Higher doses have not shown to add benefit while it could potentially cause toxic blood levels and hypercalcemia. Adequate levels of vitamin D might not be achieved with lower daily doses. Universal vitamin D supplementation starting shortly after birth, regardless of the mode of feeding and until 12 months of age, is strongly recommended. Beyond 12 months of age vitamin D supplementation is recommended only in groups of children at risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.