Observational studyBMC anesthesiology2021
Association between the modified Nutrition Risk in Critically Ill (mNUTRIC) score and clinical outcomes in the intensive care unit: a secondary analysis of a large prospective observational study.
Observational study in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Importance of nutritional assessment tools in the critically ill patient: A systematic review.Frontiers in nutrition · 2022Pooled it
- Comparison the effect of continuous and bolus enteral nutrition methods on serum albumin and prealbumin in critical ill patients: A randomized clinical trial.Journal of health, population, and nutrition · 2025Trial
- Impact of withholding early parenteral nutrition on 2-year mortality and functional outcome in critically ill adults.Intensive care medicine · 2024Trial
- Prognostic significance of malnutrition risk in elderly patients with acute kidney injury in the intensive care unit.BMC nephrology · 2022Trial
- Added Value of Quadriceps Muscle Layer Thickness to modified Nutrition Risk in the Critically Ill (mNUTRIC) Score in Predicting Clinical Outcomes in Critically Ill Patients: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Addressing metabolic demands during veno-venous extracorporeal life support: A narrative review.JPEN. Journal of parenteral and enteral nutrition · 2026Review
- Prognostic Value of mNUTRIC and CONUT Scores in ICU Patients with Intracranial Hemorrhage.Journal of clinical medicine · 2026Article
- Comparison between the NUTRIC score and modified NUTRIC score to predict hospital mortality in patients undergoing cardiac surgery: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Comparative prognostic value of nutrition-inflammation indices for 1-year mortality in elderly intensive care unit patients: a retrospective observational study based on MIMIC-IV database.BMC geriatrics · 2026Observational
- Comparative evaluation of five nutrition-inflammation indices for predicting 28-day ICU mortality in critically ill patients with bone infections: a dual-cohort study with external validation and interpretable machine learning.Frontiers in nutrition · 2026Article
- Assessment of nutritional indices for predicting clinical outcomes in critically ill elderly patients: a prospective cohort study.BMC anesthesiology · 2025Article
- Use of a Nutritional Risk Assessment Tool to Guide Early Enteral Nutrition among Mechanically Ventilated Trauma Patients.American journal of medicine open · 2025Article
- Prognostic Accuracy of Nutritional Assessment Tools in Critically-Ill COVID-19 Patients.Journal of clinical medicine · 2025Article
- Bayesian Analysis of Modified Nutrition Risk in Critically Ill (mNUTRIC) Score for Mortality Prediction in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- The Japanese Critical Care Nutrition Guideline 2024.Journal of intensive care · 2025Review
- Combined Effect of the Timing of Initiation of Nutrition and Nutrition Risk on Outcomes in a Mixed Intensive Care Unit of a Tertiary Hospital in a Middle-income Country.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Nursing-based precision assessment of nutrition and muscle status without ultrasound: a prospective observational study in mechanically ventilated neurosurgical patients.Frontiers in medicine · 2025Article
- Nutritional status as a predictor of 30-day mortality among intensive care unit patients in sub-Saharan Africa: a prospective cohort study.BMC nutrition · 2024Article
- Fasting in critical illness: the role of ketonuria - a retrospective observational study.Journal of anesthesia, analgesia and critical care · 2024Article
- Relation between nutritional status on clinical outcomes of critically ill patients: emphasizing nutritional screening tools in a prospective cohort investigation.BMC nutrition · 2024Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition in intensive care unit (ICU) patients is associated with adverse clinical outcomes. The modified nutrition risk in the critically ill score (mNUTRIC) was proposed as an appropriate nutritional assessment tool in critically ill patients, but it has not been fully demonstrated and widely used. Our study was conducted to identify the nutritional risk in ICU patients using the mNUTRIC score and explore the relationship between 28-day mortality and high mNUTRIC scores.
methodsThis study is a secondary analysis, the data were extracted from The Beijing Acute Kidney Injury Trial (BAKIT). In total, 9049 patients were admitted consecutively, and 3107 patients with complete clinical data were included in this study. We divided the study population into high nutritional risk (mNUTRIC score ≥ 5 points) and low nutritional risk (mNUTRIC score < 5 points) groups. The predictive capacity of the mNUTRIC score was studied by receiver operating characteristic (ROC) curve analysis, appropriate cut-off was identified by highest combined sensitivity and specificity using Youden's index. The significance level was set at 5%.
resultsAmong the 3107 patients, the 28-day mortality rate was 17.4% (540 patients died). Nearly 28.2% of patients admitted to the ICU were at risk of malnutrition, high nutritional risk patients were older (P < 0.001), with higher illness severity scores than low nutritional risk patients. Multivariate analysis revealed that the mNUTRIC score was an independent risk factor for 28-day mortality and mortality increased with increasing scores (p = 0.000). The calculated area under curve (AUC) for the mNUTRIC score was 0.763 (CI 0.740-0.786). According to Youden's index, we found a suitable cut-off > 4 for the mNUTRIC score to predict the 28-day mortality.
conclusionsPatients admitted to the ICU were at high risk of malnutrition, and a high mNUTRIC score was associated with increased ICU length of stay and higher mortality. More large prospective studies are needed to demonstrate the validity of this score.
trial registrationThis study was registered at www.chictr.org.cn (registration number Chi CTR-ONC-11001875 ). Registered on 14 December 2011.
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