Evidence map›Paper›PMID 34496711›Full record

ArticleOTJR : occupation, participation and health2022

Using Subthreshold Vibratory Stimulation During Poststroke Rehabilitation Therapy: A Case Series.

Amanda A Vatinno, Lucion Hall, Hannah Cox, Alison Fluharty, Catilyn Taylor, Alexandra Wease, Allison Davis, Shannon Cain, Viswanathan Ramakrishnan, Michelle Woodbury and 1 more

Abstract read
In one paragraph

Article in OTJR : occupation, participation and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amanda A VatinnoMedical University of South Carolina, Charleston, USA.ORCID 0000-0003-4987-1870
Lucion HallMedical University of South Carolina, Charleston, USA.
Hannah CoxMedical University of South Carolina, Charleston, USA.
Alison FluhartyMedical University of South Carolina, Charleston, USA.
Catilyn TaylorMedical University of South Carolina, Charleston, USA.
Alexandra WeaseMedical University of South Carolina, Charleston, USA.
Allison DavisMedical University of South Carolina, Charleston, USA.
Shannon CainMedical University of South Carolina, Charleston, USA.
Viswanathan RamakrishnanMedical University of South Carolina, Charleston, USA.
Michelle WoodburyMedical University of South Carolina, Charleston, USA.
Na Jin SeoMedical University of South Carolina, Charleston, USA.

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
South Carolina Clinical & Translational Research Institute (SCTR)TL1TR001451 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI FEGHALI-BOSTWICK, CAROL A. · 2015 to 2024
$4.6M
Role of distinctive cortical motor maps for hand muscles for recovery post strokeR01HD094731 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SEO, NA JIN · 2020 to 2024
$3.1M
NCATS NIH HHS TL1 TR001451NCATS NIH HHS UL1 TR001450NICHD NIH HHS R01 HD094731NIGMS NIH HHS P20 GM109040NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

Subthreshold vibratory stimulation to the paretic wrist has been shown to prime the sensorimotor cortex and improve 2-week upper extremity (UE) therapy outcomes. The objective of this work was to determine feasibility, safety, and preliminary efficacy of the stimulation over a typical 6-week therapy duration. Four chronic stroke survivors received stimulation during 6-week therapy. Feasibility/safety/efficacy were assessed at baseline, posttherapy, and 1-month follow-up. For feasibility, all participants wore the device throughout therapy and perceived the stimulation comfortable/safe. Regarding safety, no serious/moderate intervention-related adverse events occurred. For efficacy, all participants improved in Wolf Motor Function Test and UE use in daily living based on accelerometry and stroke impact scale. Mean improvements at posttherapy/follow-up were greater than the minimal detectable change/clinically important difference and other trials with similar therapy without stimulation. In conclusion, the stimulation was feasible/safe for 6-week use. Preliminary efficacy encourages a larger trial to further evaluate the stimulation as a therapy adjunct.

Indexed as

StrokeStroke RehabilitationAccelerometryHumansRecovery of FunctionTreatment OutcomeUpper Extremityparesispatient safetyphysical stimulationstroke rehabilitationsubliminal stimulationupper extremity

Identifiers

PMID34496711
PMCPMC8720500

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.