Evidence map›Paper›PMID 34496650›Full record

Trial reportAmerican journal of physiology. Lung cellular and molecular physiology2021

Blood fibrocytes are associated with severity and prognosis in COVID-19 pneumonia.

Mada Ghanem, Méline Homps-Legrand, Marc Garnier, Lise Morer, Tiphaine Goletto, Justine Frija-Masson, Paul-Henri Wicky, Pierre Jaquet, Catherine Bancal, Margarita Hurtado-Nedelec and 12 more

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in American journal of physiology. Lung cellular and molecular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Mada GhanemLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.ORCID 0000-0002-1363-0242
Méline Homps-LegrandLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Marc GarnierLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Lise MorerAPHP, Service de Pneumologie A, Centre de référence des Maladies Pulmonaires Rares, FHU APOLLO, Hôpital Bichat, Paris, France.
Tiphaine GolettoAPHP, Service de Pneumologie A, Centre de référence des Maladies Pulmonaires Rares, FHU APOLLO, Hôpital Bichat, Paris, France.
Justine Frija-MassonAPHP, Laboratoire d'Explorations Fonctionnelles, Hôpital Bichat, Paris, France.ORCID 0000-0001-5575-3913
Paul-Henri WickyAPHP, Service de Réanimation Médicale et Infectieuse, Hôpital Bichat, Paris, France.ORCID 0000-0002-1105-4667
Pierre JaquetAPHP, Service de Réanimation Médicale et Infectieuse, Hôpital Bichat, Paris, France.
Catherine BancalAPHP, Laboratoire d'Explorations Fonctionnelles, Hôpital Bichat, Paris, France.
Margarita Hurtado-NedelecUniversité de Paris, APHP, Laboratoire d'immunologie, Hôpital Bichat, Inserm, Paris, France.
Luc de ChaisemartinUniversité Paris-Sud, Université Paris-Saclay, APHP, Laboratoire d'immunologie, Hôpital Bichat, Paris, France, Inserm, Châtenay-Malabry, France.ORCID 0000-0001-8973-1536
Madeleine JailletLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Arnaud MailleuxLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Christophe QuesnelLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Nicolas PotéLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Marie-Pierre DebrayLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Etienne de MontmollinAPHP, Service de Réanimation Médicale et Infectieuse, Hôpital Bichat, Paris, France.
Catherine NeukirchLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Raphael BorieLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Camille TailléLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.
Bruno CrestaniLaboratoire d'excellence INFLAMEX, Université de Paris, Inserm, U1152, Paris, France.ORCID 0000-0002-2961-3455
French COVID Cohort Study Group
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRUniversité Paris-Sud · FR

Funding

Agence Nationale de la Recherche (ANR) RA-COVID-19 V12
6 · The paper itself

Abstract

Increased blood fibrocytes are associated with a poor prognosis in fibrotic lung diseases. We aimed to determine whether the percentage of circulating fibrocytes could be predictive of severity and prognosis during coronavirus disease 2019 (COVID-19) pneumonia. Blood fibrocytes were quantified by flow cytometry as CD45

Indexed as

AdultAgedAged, 80 and overAntigens, CDBlood Cell CountBlood CellsCOVID-19CytokinesFemaleHumansMaleMiddle AgedPrognosisSARS-CoV-2Serum Amyloid A ProteinSeverity of Illness IndexAntigens, CDCytokinesSerum Amyloid A ProteinCOVID-19 pneumoniafibrocyteprognosis

Identifiers

PMID34496650
PMCPMC8562948
OpenAlexW3196804048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.