ArticleArteriosclerosis, thrombosis, and vascular biology2021
Interleukin-1RA Mitigates SARS-CoV-2-Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice.
Erratum issuedOpen access · hybridAbstract read
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Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.
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32citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
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Who cites it
32 citing papers in PubMed, 38 citations in OpenAlex.
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- TRPV4/IP3R-1-mediated endothelial pyroptosis drives pulmonary microvascular endothelial permeability in endotoxin-induced acute lung injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Karacoline attenuates sepsis-induced acute lung injury by suppressing apoptosis via PPARγ-associated inhibition of JNK/ERK MAPK signaling.Respiratory research · 2026Article
- Alveolar epithelial barrier disruption by FKBP5-mediated necroptosis aggravates lung injury.Respiratory research · 2026Article
- Endothelial NEDD4L exacerbates acute lung injury by targeting A20 for ubiquitination degradation.Respiratory research · 2026Article
- USP19 alleviates LPS-induced acute lung injury via inhibiting TAK1 activation.Biology direct · 2026Article
- Pulmonary origin and risk assessment of cancer-associated thrombosis.Thrombosis journal · 2026Review
- Palmatine Attenuates Lipopolysaccharide-Induced Acute Lung Injury Via Suppression of NLRP3 Inflammasome Activation, Pyroptosis, and Metabolic Remodeling.Inflammation · 2025Article
- Prior SARS-CoV-2 infection does not increase heat stress during one hour of exercise in a hot and moderately humid environment.European journal of applied physiology · 2025Article
- IL-1β drives SARS-CoV-2-induced disease independently of the inflammasome and pyroptosis signalling.Cell death and differentiation · 2025Article
- Placenta-derived factors contribute to human iPSC-liver organoid growth.Nature communications · 2025Article
- Immune cells play a critical role in cytokine- and endotoxin-mediated endothelial permeability.PloS one · 2025Article
- Mechanistic Insights into Influenza A Virus-Induced Cell Death and Emerging Treatment Strategies.Veterinary sciences · 2024Review
- Immunobiology of COVID-19: Mechanistic and therapeutic insights from animal models.Zoological research · 2024Review
- Pyroptosis in microbial infectious diseases.Molecular biology reports · 2023Review
- Growth hormone-releasing hormone receptor antagonist MIA-602 attenuates cardiopulmonary injury induced by BSL-2 rVSV-SARS-CoV-2 in hACE2 mice.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The role of cell death in SARS-CoV-2 infection.Signal transduction and targeted therapy · 2023Review
- Temporal and Spatial Patterns of Inflammation and Tissue Injury in Patients with Postoperative Respiratory Failure after Lung Resection Surgery: A Nested Case-Control Study.International journal of molecular sciences · 2023Article
- Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies.Acta pharmacologica Sinica · 2023Review
- Molecular mechanisms and roles of pyroptosis in acute lung injury.Chinese medical journal · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 1 country.
Shiqin XiongDepartment of Pharmacology and Regenerative Medicine and the Center for Lung and Vascular Biology (S.X., L.Z., J.R., A.B.M.), University of Illinois College of Medicine at Chicago.
Lianghui ZhangDepartment of Pharmacology and Regenerative Medicine and the Center for Lung and Vascular Biology (S.X., L.Z., J.R., A.B.M.), University of Illinois College of Medicine at Chicago.
Justin M RichnerDepartment of Microbiology and Immunology (J.M.R., J.C.), University of Illinois College of Medicine at Chicago.
Jake ClassDepartment of Microbiology and Immunology (J.M.R., J.C.), University of Illinois College of Medicine at Chicago.ORCID 0000-0003-1928-5950
Jalees RehmanDepartment of Pharmacology and Regenerative Medicine and the Center for Lung and Vascular Biology (S.X., L.Z., J.R., A.B.M.), University of Illinois College of Medicine at Chicago.
Asrar B MalikDepartment of Pharmacology and Regenerative Medicine and the Center for Lung and Vascular Biology (S.X., L.Z., J.R., A.B.M.), University of Illinois College of Medicine at Chicago.ORCID 0000-0002-8205-7128
Illinois College · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USUniversity of Illinois Chicago · US
Funding
TRPC6 Regulation of Lung Endothelial Barrier FunctionP01HL060678 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALIK, ASRAR B. · 2000 to 2020
$40.1MTRAINING PROGRAM IN LUNG BIOLOGY AND PATHOBIOLOGYT32HL007829 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOLLY MEHTA · 1995 to 2026
$15.6MEndothelial Regeneration Following Lung Vascular InjuryR01HL118068 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALIK, ASRAR B., REHMAN, JALEES · 2014 to 2017
$2.4MNanoparticle Targeting of Neutrophil Subpopulations in Inflammatory Lung InjuryR01HL149300 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALIK, ASRAR B., REHMAN, JALEES · 2019 to 2022
$2.4MAmplification Mechanisms of Lung Endothelial Inflammation During Acute Lung InjuryR01HL152515 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REHMAN, JALEES · 2021 to 2024
$2.3MEndothelial antigen presentation to T cells as a pathogenic mechanism in influenza-induced acute lung injury.R01HL157489 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHANG, LIANGHUI · 2021 to 2025
$2.0MEndothelial Instruction of Macrophage Fate in Inflammatory InjuryR01HL154538 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI REHMAN, JALEES · 2021 to 2021
$128kNHLBI NIH HHS P01 HL060678NHLBI NIH HHS R01 HL118068NHLBI NIH HHS R01 HL149300NHLBI NIH HHS R01 HL152515NHLBI NIH HHS R01 HL154538NHLBI NIH HHS R01 HL157489NHLBI NIH HHS T32 HL007829
Abstract
[Figure: see text].
Indexed as
COVID-19 Drug TreatmentAnimalsAntigens, CDCadherin 5CadherinsCapillary PermeabilityCaspase 1COVID-19Disease Models, AnimalDown-RegulationEdemaEndothelium, VascularEnzyme ActivationFibrosisInterleukin 1 Receptor Antagonist ProteinMiceAntigens, CDCadherin 5CadherinsCasp1 protein, mouseCaspase 1Interleukin 1 Receptor Antagonist ProteinNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseReceptors, Interleukin-1edemaiesinterleukin-1pyroptosisSARS-CoV-2vascular system injur
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.