ArticleJournal of biomechanics2021
Modeling acute ischemic stroke recanalization through cyclic aspiration.
Article in Journal of biomechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Development, characterization, and curve fitting of rate-dependent models of calcified cerebral embolus analogs for acute ischemic stroke.Biomechanics and modeling in mechanobiology · 2025Article
- Characterization of the In Situ Stress State of Blood Clots in Ischemic Stroke: The Effect of Initial Conditions and Arterial Interaction.International journal for numerical methods in biomedical engineering · 2025Article
- A hyper-viscoelastic uniaxial characterization of collagenous embolus analogs in acute ischemic stroke.Journal of the mechanical behavior of biomedical materials · 2024Article
- Current Approaches and Methods to Understand Acute Ischemic Stroke Treatment Using Aspiration Thrombectomy.Cardiovascular engineering and technology · 2024Review
- Computational analysis of effects of clot length on Acute ischemic stroke recanalization under different cyclic aspiration loading conditions.International journal for numerical methods in biomedical engineering · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
We model the deformation of a thromboembolus lodged in a cerebral artery under the application of aspiration pressure as it would be provided by an aspiration catheter during a mechanical thrombectomy procedure. The system considered consists of (i) a clot modeled as a viscoelastic solid; (ii) an artery modeled as a hyperelastic solid; and (iii) a viscoelastic cohesive interface between the clot and the artery. For the chosen system and geometry, we show that the application of aspiration pressure results in the impingement of the thrombus against the inner arterial wall near the aspiration location. Conditions leading to interfacial failure are nucleated at the distal end of the clot and, depending on the details of the loading conditions, propagate toward the proximal end. The results provide useful information in identifying the circumstances that play a decisive role for clot removal by aspiration alone.
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Registered trials
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