Evidence map›Paper›PMID 34496235›Full record

ArticleCell reports2021

Specific impact of β5t on proteasome subunit composition in cortical thymic epithelial cells.

Izumi Ohigashi, Yousuke Takahama

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. The thymoproteasome in shaping the CD8Current opinion in immunology · 2023
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Izumi OhigashiDivision of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima 770-8503, Japan.
Yousuke TakahamaThymus Biology Section, Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: yousuke.takahama@nih.gov.
Tokushima University · JP

Funding

Thymus biologyZIABC011806 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TAKAHAMA, YOUSUKE · 2018 to 2025
$13.5M
Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA BC011806
6 · The paper itself

Abstract

β5t is a cortical thymic epithelial cell (cTEC)-specific component of the thymoproteasome, which is essential for the optimal production of functionally competent CD8

Indexed as

CD8-Positive T-LymphocytesProteasome Endopeptidase ComplexEpithelial CellsHistocompatibility Antigens Class IThymocytesHistocompatibility Antigens Class IProteasome Endopeptidase ComplexCortical thymic epithelial cellPositive selectionProteasomePsmb11T cell developmentThymoproteasomeThymusβ5t

Identifiers

PMID34496235
PMCPMC8442848
OpenAlexW3198646114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.