Evidence map›Paper›PMID 34495680›Full record

ArticleMolecular biology of the cell2021

Modeling and analysis of the macronutrient signaling network in budding yeast.

Amogh P Jalihal, Pavel Kraikivski, T M Murali, John J Tyson

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Mathematical Models of Death Signaling Networks.Entropy (Basel, Switzerland) · 2022
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Amogh P JalihalGenetics, Bioinformatics, and Computational Biology PhD Program.
Pavel KraikivskiDivision of Systems Biology, Academy of Integrated Science, Virginia Tech, Blacksburg, VA 24061.
T M MuraliDepartment of Computer Science, Virginia Tech, Blacksburg, VA 24061.
John J TysonDivision of Systems Biology, Academy of Integrated Science, Virginia Tech, Blacksburg, VA 24061.
Virginia Tech · USInstitut thématique Génétique, génomique et bioinformatique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptive modulation of the global cellular growth state of unicellular organisms is crucial for their survival in fluctuating nutrient environments. Because these organisms must be able to respond reliably to ever varying and unpredictable nutritional conditions, their nutrient signaling networks must have a certain inbuilt robustness. In eukaryotes, such as the budding yeast

Indexed as

Carrier ProteinsCell CycleComputational BiologyEatingGene ExpressionGene Expression Regulation, FungalModels, TheoreticalNitrogenNutrientsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionTranscription FactorsTranscriptomeCarrier ProteinsNitrogenNutrientsSaccharomyces cerevisiae ProteinsTranscription Factors

Identifiers

PMID34495680
PMCPMC8693975
OpenAlexW3197332856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.