Evidence map›Paper›PMID 34495452›Full record

ReviewCurrent heart failure reports2021

Optimal CRT Implantation-Where and How To Place the Left-Ventricular Lead?

Christian Butter, Christian Georgi, Martin Stockburger

Registry-linked trialAbstract readReview
In one paragraph

Review in Current heart failure reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06342492 (Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06342492 recruitingnot on this mapstarted 2023, after this paper: background citation

Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure

TypeobservationalSponsorKansas City Heart Rhythm Research FoundationRan2023 to 2024Enrolled100ConditionsHeart Failure With Reduced Ejection FractionArmsCoronary Sinus Lead Revision
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Computational Modelling Enabling In Silico Trials for Cardiac Physiologic Pacing.Journal of cardiovascular translational research · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christian ButterDepartment of Cardiology, Heart Center Brandenburg, University Hospital Brandenburg, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany. christian.butter@immanuelalbertinen.de.
Christian GeorgiDepartment of Cardiology, Heart Center Brandenburg, University Hospital Brandenburg, Brandenburg Medical School Theodor Fontane, Brandenburg, Germany.ORCID http://orcid.org/0000-0002-5991-2333
Martin StockburgerDepartment of Internal Medicine/Cardiology, Havelland Kliniken GmbH, Nauen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewCardiac resynchronization therapy (CRT) represents a well-established and effective non-pharmaceutical heart failure (HF) treatment in selected patients. Still, a significant number of patients remain CRT non-responders. An optimal placement of the left ventricular (LV) lead appears crucial for the intended hemodynamic and hence clinical improvement. A well-localized target area and tools that help to achieve successful lead implantation seem to be of utmost importance to reach an optimal CRT effect. RECENT

findingsRecent studies suggest previous multimodal imaging (CT/cMRI/ECG torso) to guide intraprocedural LV lead placement. Relevant benefit compared to empirical lead optimization is still a matter of debate. Technical improvements in leads and algorithms (e.g., multipoint pacing (MPP), adaptive algorithms) promise higher procedural success. Recently emerging alternatives for ventricular synchronization such as conduction system pacing (CSP), LV endocardial pacing, or leadless pacing challenge classical biventricular pacing. This article reviews current strategies for a successful planning, implementation, and validation of the optimal CRT implantation. Pre-implant imaging modalities offer promising assistance for complex cases; empirical lead positioning and intraoperative testing remain the cornerstone in most cases and ensure a successful CRT effect.

Indexed as

Cardiac Resynchronization TherapyHeart FailureHeart VentriclesHemodynamicsHumansTreatment OutcomeAcute hemodynamic responseCardiac resynchronization therapyCoronary sinusLead implantationMultimodal imaging

Identifiers

PMID34495452
PMCPMC8484220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.