ArticleRevista da Sociedade Brasileira de Medicina Tropical2021
Nutritional status and vitamin A and zinc levels in patients with kala-azar in Piauí, Brazil.
Article in Revista da Sociedade Brasileira de Medicina Tropical, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 7 citations in OpenAlex.
- Global burden of leishmaniasis, 1990-2021: systematic analysis of the global burden of disease study.International journal for equity in health · 2025Article
- First documented case of visceral leishmaniasis with rare colonic involvement in an immunocompetent adult in Slovakia.BMC infectious diseases · 2025Article
- Global Dilemma and Needs Assessment Toward Achieving Sustainable Development Goals in Controlling Leishmaniasis.Journal of epidemiology and global health · 2024Review
- From Infection to Death: An Overview of the Pathogenesis of Visceral Leishmaniasis.Pathogens (Basel, Switzerland) · 2023Review
- Immune Impairment Associated with Vitamin A Deficiency: Insights from Clinical Studies and Animal Model Research.Nutrients · 2022Review
- Article
- Assessment of nutritional status among post-kala-azar dermal leishmaniasis patients in endemic areas of northern West Bengal, India.Tropical parasitologyArticle
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Authors and funding
11 authors at 3 institutions in 1 country.
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Abstract
introductionMalnutrition and kala-azar (or visceral leishmaniasis) are significant public health problems in different parts of the world. Immunity and susceptibility to infectious and parasitic diseases are directly linked to the host's nutritional state, but little is known about the interaction between nutrition and kala-azar. This study aimed to evaluate nutritional status with kala-azar and correlate these findings with the clinical and laboratory manifestations of the disease, and zinc and retinol levels.
methodsThis was a cross-sectional study of 139 patients with kala-azar. Nutritional status classification was performed according to international recommendations. Parametric or nonparametric tests were applied whenever indicated in a two-sided test with a 5% significance level.
resultsWeight loss and malnutrition were more frequent in adults. Body mass index-for-age, fat area of the arm, and upper arm muscle area were significantly associated with probability of death. The presence of human immunodeficiency virus, hepatomegaly, and splenomegaly was correlated with nutritional assessment. Blood leukocyte and lymphocyte, serum creatine, and vitamin A levels were significantly higher in adult men. Vitamin A levels were highly associated with the level of hemoglobin and C-reactive protein (CRP) in multivariate analysis. All patients had reduced plasma zinc levels, but this finding had no association with the outcome variables.
conclusionsMalnutrition was correlated with severe disease and was more prevalent in older people with kala-azar. Vitamin A deficiency was associated with hemoglobin and CRP. Zinc levels were reduced in patients with kala-azar.
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