Trial reportJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2021
The impact of the stratification by degree of clinical severity and abandonment risk of tuberculosis treatment.
Trial report in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- [Tuberculosis in childhood and adolescence: prevalence and factors associated with treatment abandonment].Cadernos de saude publica · 2024Article
- Factors Associated with Tuberculosis Outcome in a Hyperendemic City in the North of Brazil.Healthcare (Basel, Switzerland) · 2023Article
- Access of people with pulmonary tuberculosis to government programs: Primary Care professionals' perceptions.Revista brasileira de enfermagem · 2023Article
- High risk of unsuccessful treatment outcome in migrant population with tuberculosis: Data from three Italian hospitals.Frontiers in public health · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEvaluate the impact of the instrument of the "Stratification by Degree of Clinical Severity and Abandonment Risk of Tuberculosis Treatment" (SRTB) on the tuberculosis outcome.
methodsThis study was a pragmatic clinical trial involving patients with a confirmed diagnosis of tuberculosis treated at one of the 152 primary health care units in the city of Belo Horizonte, Brazil, between May of 2016 and April of 2017. Cluster areas for tuberculosis were identified, and the units and their respective patients were divided into intervention (use of SRTB) and nonintervention groups.
resultsThe total sample comprised 432 participants, 223 and 209 of whom being allocated to the nonintervention and intervention groups, respectively. The risk of treatment abandonment in the nonintervention group was significantly higher than was that in the intervention group (OR = 15.010; p < 0.001), regardless of the number of risk factors identified. Kaplan-Meier curves showed a hazard ratio of 0.0753 (p < 0.001).
conclusionsThe SRTB instrument was effective in reducing abandonment of tuberculosis treatment, regardless of the number of risk factors for that. This instrument is rapid and easy to use, and can be adapted to different realities. Its application showed characteristics predisposing to a non-adherence to the treatment and established bases to mitigate its impact.
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