ArticleJournal of applied oral science : revista FOB2021
Influence of caries activity and number of saliva donors: mineral and microbiological responses in a microcosm biofilm model.
Article in Journal of applied oral science : revista FOB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Black Cumin Seed Oil Disrupts Structural Biomass and Attenuates Porphyrin-Associated Maturation in Mature Oral Microcosm Biofilms: An In Vitro Study.Biomedicines · 2026Article
- Bioactivity of Glass Carbomer Versus Conventional GICs in Sound Enamel and Dentine: A 12-Month SEM-EDS Study.Materials (Basel, Switzerland) · 2025Article
- Antimicrobial Efficacy and Biocompatibility of a Denture Cleanser ContainingBiomedicines · 2025Article
- Influence of irradiated dentin, biofilm and different artificial saliva formulations on root dentin demineralization.Heliyon · 2024Article
- Addition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities.Microbiome · 2023Article
- Association of polymicrobial interactions with dental caries development and prevention.Frontiers in microbiology · 2023Review
- Variation in adhesion ofKorean journal of orthodontics · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivethis study evaluated the mineral and microbiological response of biofilms originating from different types of saliva inoculum with distinct levels of caries activity. METHODOLOGY: the biofilms grown over enamel specimens originated from saliva collected from a single donor or five donors with two distinct levels of caries activity (caries-active and caries-free) or from pooling saliva from ten donors (five caries-active and five caries-free). The percentage surface hardness change (%SHC) and microbiological counts served as outcome variables.
resultsthe caries activity of donors did not affect the %SHC values. Inoculum from five donors compared to a single donor showed higher %SHC values (p=0.019). Higher lactobacilli counts were observed when saliva from caries-active donors was used as the inoculum (p=0.017). Pooled saliva from both caries activity levels showed higher mutans streptococci counts (p<0.017).
conclusionOverall, pooled saliva increased the mineral response of the derived biofilms, but all the inoculum conditions formed cariogenic biofilms and caries lesions independently of caries activity.
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