ArticleMicrobiology spectrum2021
Dietary Supplementation of Inulin Ameliorates Subclinical Mastitis via Regulation of Rumen Microbial Community and Metabolites in Dairy Cows.
Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 124 citations in OpenAlex.
- Global spatiotemporal patterns of bovine mastitis pathogens from 2000 to 2025: a meta-analysis for precision dairy health.Journal of animal science and biotechnology · 2026Article
- Effects of Replacing Alfalfa withAnimals : an open access journal from MDPI · 2026Article
- Harnessing microbial metabolism and nutrition to target the gut-mammary axis for better livestock production and health.iMetaOmics · 2026Review
- High-dose phytosterols supplementation improves lactation performance, modulates rumen microbiota, and reduces methane emission intensity in mid-lactation Holstein dairy cows.Veterinary world · 2026Article
- Microbial landscapes in dairy cow diseases: from localized dysbiosis to inter-organ axes.NPJ biofilms and microbiomes · 2026Review
- Prevalence, Virulence, and Pathogenic Mechanisms of Mastitis-AssociatedVeterinary sciences · 2026Review
- Thermal Image-Based Artificial Neural Network Approach to Determine Mastitis Detection in Holstein Dairy Cattle.Animals : an open access journal from MDPI · 2026Article
- Feeding different proportion of oat silage in feedlot diets: effects on rumen function and meat quality of Tibetan sheep.AMB Express · 2026Article
- Machine learning reveals targets ofFrontiers in immunology · 2026Article
- Phytosphingosine contributes gut microbiota metabolism to alleviate low-grade endotoxemia-induced mastitis.Microbiome · 2025Article
- Targeting the Gut-Mammary Axis for Understanding Mastitis Pathogenesis and Therapeutic Strategies.Veterinary sciences · 2025Review
- Vitamin D3 Improves Hypothalamic-Pituitary-Adrenal Axis Function, Immunological Responses, and Gut Dysbiosis in Sleep Desynchrony.Brain and behavior · 2025Article
- Ruminal dysbiosis-induced mastitis: new insight into the pathogenesis of mastitis.Journal of animal science and biotechnology · 2025Review
- Puerarin attenuatesMicrobiology spectrum · 2025Article
- DietaryAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Multidimensional Phenotypic and Microbiome Studies Uncover an Association Between Reduced Feed Efficiency in Sheep During Mycoplasmal Pneumonia and Microbial Crosstalk Within the Rumen-Lung Axis.Veterinary sciences · 2025Article
- Effects of Grazing in a Low Deciduous Forest on Rumen Microbiota and Volatile Fatty Acid Production in Lambs.Animals : an open access journal from MDPI · 2025Article
- Rumen microbes affect the somatic cell counts of dairy cows by modulating glutathione metabolism.mSystems · 2025Article
- Physiological and Microbial Community Dynamics in Does During Mid-Gestation to Lactation and Their Impact on the Growth, Immune Function, and Microbiome Transmission of Offspring Kids.Animals : an open access journal from MDPI · 2025Article
- Growth Performance and Gut Health of Cold-Stressed Broilers in Response to Supplementation with a Combination of Sodium Butyrate and Vitamin D3.Animals : an open access journal from MDPI · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subclinical mastitis (SCM) is one of the highly infectious diseases in dairy cows with the characteristics of high incidence and nonvisible clinical symptoms. The gastrointestinal microbiota is closely related to mastitis. Inulin is a prebiotic fiber with functions in improving intestinal microbial communities and enhancing the host's immunity. However, the impact of dietary inulin on the rumen inner environment remains unknown. The current study investigated whether inulin could relieve SCM by affecting the profiles of ruminal bacterial and metabolites in dairy cows. Inulin inclusion rates were 0, 100, 200, 300, and 400 g/day per cow, respectively. Inulin increased milk yield, milk protein, and lactose and reduced the somatic cell counts (SCC) in milk. In serum, the concentration of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-8, tumor necrosis factor α (TNF-α), and malondialdehyde (MDA) were decreased, and IL-4 and superoxide dismutase (SOD) were increased. Meanwhile, inulin increased the concentration of propionate, butyrate, and lactic acid (LA), while it decreased NH
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.