Trial reportObesity (Silver Spring, Md.)2021
A Randomized Trial Evaluating Exercise for the Prevention of Weight Regain.
Trial report in Obesity (Silver Spring, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of exercise interventions on weight regain after weight loss: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Role of Physical Activity in Obesity Treatment and Cardiometabolic Health: A Scientific Statement From the American Heart Association.Circulation · 2026Review
- Association Between Wake-Time Movement Behaviors and Weight Loss Maintenance.Obesity (Silver Spring, Md.) · 2026Article
- Article
- The Role of Physical Activity in Minimizing Recurrence of Weight Gain Following Metabolic and Bariatric Surgery: Current Evidence and Suggestions for Advancing Future Research.Current obesity reports · 2025Review
- Intraday relations between physical activity and energy intake among behavioral weight loss participants.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- Evidence-Based Eating Patterns and Behavior Changes to Limit Excessive Gestational Weight Gain: A Scoping Review.International journal of environmental research and public health · 2023Article
- Short- and Long-Term Weight Loss Among Women Is Unrelated to Completed Exercise Within an Obesity Intervention Focused on Self-Regulation.The Permanente journal · 2023Article
- Obesity-induced and weight-loss-induced physiological factors affecting weight regain.Nature reviews. Endocrinology · 2023Review
- Physical activity and exercise for weight loss and maintenance in people living with obesity.Reviews in endocrine & metabolic disorders · 2023Review
- Pre-post intervention exploring cognitive function and relationships with weight loss, intervention adherence and dropout.Health psychology and behavioral medicine · 2023Article
- Behavioral Weight Loss and Maintenance: A 25-Year Research Program Informing Innovative Programming.The Permanente journal · 2022Review
- Pathological Significance of Macrophages in Erectile Dysfunction Including Peyronie's Disease.Biomedicines · 2021Review
- Effect of exercise training on weight loss, body composition changes, and weight maintenance in adults with overweight or obesity: An overview of 12 systematic reviews and 149 studies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Review
- Physical Activity, Weight Loss, and Weight Maintenance in the DiOGenes Multicenter Trial.Frontiers in nutrition · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectiveThis study aimed to evaluate the effectiveness of three levels of exercise on weight regain subsequent to clinically meaningful weight loss (WL).
methodsAdults with overweight or obesity (n = 298) initiated a 3-month behavioral WL intervention, which included reduced energy intake, increased exercise, and weekly behavioral counseling. Participants achieving ≥5% WL (n = 235) began a 12-month behavioral WL maintenance intervention and were randomized to 150 min/wk (n = 76), 225 min/wk (n = 80), or 300 min/wk (n = 79) of partially supervised moderate-to-vigorous-intensity exercise.
resultsParticipants randomized to 150, 225, and 300 minutes of exercise completed 129 ± 30, 153 ± 49 and 179 ± 62 min/wk of exercise (supervised + unsupervised), respectively. Mean WL at 3 months (9.5 ± 3.1 kg) was similar across randomized groups (P = 0.68). Weight change across 12 months was 1.1 ± 6.5 kg, 3.2 ± 5.7 kg, and 2.8 ± 6.9 kg in the 150, 225, and 300 min/wk groups, respectively. Intent-to-treat analysis revealed no significant overall trend across the three treatment groups (P = 0.09), effects for group (P = 0.08), or sex (P = 0.21).
conclusionsThis study found no evidence for an association between the volume of moderate-to-vigorous-intensity exercise and weight regain across 12 months following clinically relevant WL. Further, results suggest that exercise volumes lower than those currently recommended for WL maintenance, when completed in conjunction with a behavioral weight-maintenance intervention, may minimize weight regain over 12 months.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.