Evidence map›Paper›PMID 34494230›Full record

ArticleObesity surgery2021

Esophageal Cancer After Bariatric Surgery: Increasing Prevalence and Treatment Strategies.

Victor D Plat, Anne Kasteleijn, Jan Willem M Greve, Misha D P Luyer, Suzanne S Gisbertz, Ahmet Demirkiran, Freek Daams

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Obesity surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Article
  6. Review
  7. Article
  8. Review
  9. Treatment of esophageal adenocarcinoma in patients with a history of bariatric surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2024
    Article
  10. THE GROWING EVIDENCE OF THE RELATIONSHIP BETWEEN OBESITY AND CANCER AND THE ROLE OF BARIATRIC SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2024
    Review
  11. Reduced risk of de novo Barrett esophagus after bariatric surgery: a national database study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024
    Article
  12. Article
  13. The Novel Conduit: Challenges of Esophagectomy After Bariatric Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  14. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Victor D PlatDepartment of Gastrointestinal Surgery, Amsterdam UMC, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, Postbus 7075, 1007 MB, Amsterdam, The Netherlands.
Anne KasteleijnDepartment of Gastrointestinal Surgery, Amsterdam UMC, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, Postbus 7075, 1007 MB, Amsterdam, The Netherlands.
Jan Willem M GreveDepartment of Gastrointestinal Surgery, Zuyderland Medical Center, Heerlen, The Netherlands.
Misha D P LuyerDepartment of Gastrointestinal Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Suzanne S GisbertzDepartment of Gastrointestinal Surgery, Amsterdam UMC, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, Postbus 7075, 1007 MB, Amsterdam, The Netherlands.
Ahmet DemirkiranDepartment of Gastrointestinal Surgery, Rode Kruis Hospital, Beverwijk, The Netherlands.
Freek DaamsDepartment of Gastrointestinal Surgery, Amsterdam UMC, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, Postbus 7075, 1007 MB, Amsterdam, The Netherlands. f.daams@amsterdamumc.nl.ORCID http://orcid.org/0000-0001-6323-6342
Vrije Universiteit Amsterdam · NLAmsterdam Neuroscience · NLMaastricht University · NLRadboud University Nijmegen · NLRode Kruis Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe number of bariatric procedures has increased exponentially over the last 20 years. On the background of ever-increasing incidence of esophageal malignancies, the altered anatomy after bariatric surgery poses challenges in treatment of these cancers. In this study, an epidemiological estimate is presented for the future magnitude of this problem and treatment options are described in a retrospective multicenter cohort.

methodsThe number of bariatric procedures, esophageal cancer incidence, and mortality rates of the general population were used for epidemiological estimates. A retrospective multicenter cohort was composed; patients were treated in three large oncological centers with a high upper gastrointestinal cancer caseload. Consecutive patients with preceding bariatric surgery who developed esophageal cancer between 2014 and 2019 were included.

resultsApproximately 3200 out of 6.4 million post bariatric surgery patients are estimated to have developed esophageal cancer between 1998 and 2018 worldwide. In a multicenter cohort, 15 patients with esophageal cancer or Barrett's esophagus and preceding bariatric surgery were identified. The majority of patients had a history of Roux-en-Y gastric bypass (46.7%) and had an adenocarcinoma of the distal esophagus (60%). Seven patients received curative surgical treatment, five of whom are still alive at last follow-up (median follow-up 2 years, no loss to follow-up).

conclusionBased on worldwide data, esophageal cancer development following bariatric surgery has increased over the past decades. Treatment of patients with esophageal cancer after bariatric surgery is challenging and requires a highly individualized approach in which optimal treatment and anatomical limitations are carefully balanced.

Indexed as

Bariatric SurgeryEsophageal NeoplasmsGastric BypassObesity, MorbidHumansPrevalenceRetrospective StudiesBariatric surgeryEsophageal cancerEsophagectomyTreatment

Identifiers

PMID34494230
PMCPMC8490213
OpenAlexW3198687753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.