Evidence map›Paper›PMID 34494118›Full record

ArticleThe Journal of nutrition2021

Disparities in Risks of Inadequate and Excessive Intake of Micronutrients during Pregnancy.

Katherine A Sauder, Robyn N Harte, Brandy M Ringham, Patricia M Guenther, Regan L Bailey, Akram Alshawabkeh, José F Cordero, Anne L Dunlop, Erin P Ferranti, Amy J Elliott and 28 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 1 country.

Katherine A SauderLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-8473-8015
Robyn N HarteLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Brandy M RinghamLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Patricia M GuentherDepartment of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA.
Regan L BaileyDepartment of Nutrition Science, Purdue University, West Lafayette, IN, USA.
Akram AlshawabkehCollege of Engineering, Northeastern University, Boston, MA, USA.
José F CorderoDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA.
Anne L DunlopNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Erin P FerrantiNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.
Amy J ElliottAvera Research Institute, Sioux Falls, SD, USA.
Diane C MitchellDepartment of Nutritional Sciences, Penn State University, University Park, PA, USA.
Monique M HeddersonDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Lyndsay A AvalosDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Yeyi ZhuDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.ORCID 0000-0002-7296-738X
Carrie V BretonLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Leda ChatziDepartment of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Jin RanDepartment of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Irva Hertz-PicciottoDepartment of Public Health Sciences, School of Medicine, University of California, Davis, Davis, CA, USA.
Margaret R KaragasDepartment of Epidemiology, Dartmouth College, Hanover, NH, USA.
Vicki SayarathDepartment of Epidemiology, Dartmouth College, Hanover, NH, USA.
Joseph HooverCommunity Environmental Health Program, College of Pharmacy at the University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Debra MacKenzieCommunity Environmental Health Program, College of Pharmacy at the University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Kristen LyallAJ Drexel Autism Institute, Drexel University, Philadelphia, PA, USA.
Rebecca J SchmidtDepartment of Public Health Sciences, School of Medicine, University of California, Davis, Davis, CA, USA.
Thomas G O'ConnorDepartments of Psychiatry, Psychology, Neuroscience, and Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA.
Emily S BarrettDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA.
Karen M SwitkowskiDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Sarah S ComstockDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA.
Jean M KerverDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
Leonardo TrasandeDepartment of Pediatrics, New York University Grossman School of Medicine, New York, NY, USA.
Frances A TylavskyDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.ORCID 0000-0002-9479-8003
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Srimathi KannanDepartment of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, USA.
Noel T MuellerDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Diane J CatellierRTI International, Research Triangle Park, NC, USA.
Deborah H GlueckLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Dana DabeleaLifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0001-9514-8929
Program Collaborators for Environmental influences on Child Health Outcomes (ECHO)
University of Colorado Anschutz Medical Campus · USJohns Hopkins University · USKaiser Permanente · USDartmouth College · USEmory University · USMichigan State University · USUniversity of California, Davis · USUniversity of New Mexico · USUniversity of Southern California · USAvera Health · USDrexel University · USHarvard University · USIcahn School of Medicine at Mount Sinai · USNew York University · USNortheastern University · USPennsylvania State University · USPurdue University West Lafayette · USRTI International · USRutgers, The State University of New Jersey · USUniversity of Georgia · US

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI JUNFENG ZHANG · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
The NYU Children’s Health & Environment Study: an ECHO CohortUH3OD023305 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Akhgar Ghassabian, Leonardo Trasande · 2018 to 2026
$59.5M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
VARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 1995 to 2019
$52.0M
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Research Experiences and Training Coordination CoreP42ES017198 · NIEHS · NORTHEASTERN UNIVERSITY · PI ALSHAWABKEH, AKRAM N · 2010 to 2024
$38.6M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
ATSDR CDC HHS U01 TS000135Autism Speaks AS5938NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR002535NCATS NIH HHS UL1 TR004419NCI NIH HHS U01 CA215834NHLBI NIH HHS K01 HL141589NICHD NIH HHS R01 HD034568NICHD NIH HHS U01 HD045935NIDDK NIH HHS K01 DK120807NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK076648NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P30 ES023513NIEHS NIH HHS P42 ES007373NIEHS NIH HHS P42 ES017198NIEHS NIH HHS P50 ES026086NIEHS NIH HHS R01 ES016443NIEHS NIH HHS R01 ES025574NIEHS NIH HHS R01 ES031701NIEHS NIH HHS R21 ES021318NIEHS NIH HHS R24 ES028533NIEHS NIH HHS R24 ES029490NIGMS NIH HHS R01 GM121081NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023271NIH HHS UG3 OD023285NIH HHS UG3 OD023318NIH HHS UH3 OD023248NIH HHS UH3 OD023251NIH HHS UH3 OD023271NIH HHS UH3 OD023275NIH HHS UH3 OD023279NIH HHS UH3 OD023285NIH HHS UH3 OD023286NIH HHS UH3 OD023287NIH HHS UH3 OD023305NIH HHS UH3 OD023318NIH HHS UH3 OD023337NIH HHS UH3 OD023344NIH HHS UH3 OD023349NIH HHS UH3 OD023365NINR NIH HHS K01 NR017664NINR NIH HHS R01 NR014800
6 · The paper itself

Abstract

backgroundInadequate or excessive intake of micronutrients in pregnancy has potential to negatively impact maternal/offspring health outcomes.

objectiveThe aim was to compare risks of inadequate or excessive micronutrient intake in diverse females with singleton pregnancies by strata of maternal age, race/ethnicity, education, and prepregnancy BMI.

methodsFifteen observational cohorts in the US Environmental influences on Child Health Outcomes (ECHO) Consortium assessed participant dietary intake with 24-h dietary recalls (n = 1910) or food-frequency questionnaires (n = 7891) from 1999-2019. We compared the distributions of usual intake of 19 micronutrients from food alone (15 cohorts; n = 9801) and food plus dietary supplements (10 cohorts with supplement data; n = 7082) to estimate the proportion with usual daily intakes below their age-specific daily Estimated Average Requirement (EAR), above their Adequate Intake (AI), and above their Tolerable Upper Intake Level (UL), overall and within sociodemographic and anthropometric subgroups.

resultsRisk of inadequate intake from food alone ranged from 0% to 87%, depending on the micronutrient and assessment methodology. When dietary supplements were included, some women were below the EAR for vitamin D (20-38%), vitamin E (17-22%), and magnesium (39-41%); some women were above the AI for vitamin K (63-75%), choline (7%), and potassium (37-53%); and some were above the UL for folic acid (32-51%), iron (39-40%), and zinc (19-20%). Highest risks for inadequate intakes were observed among participants with age 14-18 y (6 nutrients), non-White race or Hispanic ethnicity (10 nutrients), less than a high school education (9 nutrients), or obesity (9 nutrients).

conclusionsImproved diet quality is needed for most pregnant females. Even with dietary supplement use, >20% of participants were at risk of inadequate intake of ≥1 micronutrients, especially in some population subgroups. Pregnancy may be a window of opportunity to address disparities in micronutrient intake that could contribute to intergenerational health inequalities.

Indexed as

MicronutrientsVitaminsAdolescentChildDietDietary SupplementsFemaleHumansNutritional RequirementsPregnancyMicronutrientsVitaminsdietDietary Reference Intakesdietary supplementsmicronutrientsmineralspregnancyvitamins

Identifiers

PMID34494118
PMCPMC8564697
OpenAlexW3198261029

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.