Evidence map›Paper›PMID 34493997›Full record

ArticleEClinicalMedicine2021

Racial and ethnic disparity in clinical outcomes among patients with confirmed COVID-19 infection in a large US electronic health record database.

Ami R Buikema, Paul Buzinec, Misti L Paudel, Katherine Andrade, Jonathan C Johnson, Yvette M Edmonds, Sumit K Jhamb, Benjamin Chastek, Harish Raja, Feng Cao and 6 more

Open access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Telehealth Use and Health Equity for Mental Health and Substance Use Disorder During the COVID-19 Pandemic: A Systematic Review.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2024
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  4. Article
  5. Racial and Ethnic Disparities in COVID-19 Treatments in the United States.Journal of racial and ethnic health disparities · 2025
    Article
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  8. Disparities in COVID-19-Related Mortality Among Older Adults With Alzheimer's Disease and Related Dementias: Variations Over Time.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Ami R BuikemaOptum, Eden Prairie, MN, USA.
Paul BuzinecOptum, Eden Prairie, MN, USA.
Misti L PaudelOptum, Eden Prairie, MN, USA.
Katherine AndradeOptum, Eden Prairie, MN, USA.
Jonathan C JohnsonOptum, Eden Prairie, MN, USA.
Yvette M EdmondsOptum, Eden Prairie, MN, USA.
Sumit K JhambOptum, Noida, India.
Benjamin ChastekOptum, Eden Prairie, MN, USA.
Harish RajaOptum, Boston, MA, USA.
Feng CaoOptum, Eden Prairie, MN, USA.
Erin M HulbertOptum, Eden Prairie, MN, USA.
Stephanie KorrerOptum, Eden Prairie, MN, USA.
Dibyajyoti MazumderOptum, Noida, India.
Jerry SeareOptum, Eden Prairie, MN, USA.
Brian K SolowOptum, Irvine, CA, USA.
U Michael CurrieUnitedHealth Group, Minnetonka, MN, USA.
Optum (United States) · USNew England College of Optometry · USUnitedHealth Group (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRacial and ethnic minority groups have been disproportionately affected by the US coronavirus disease 2019 (COVID-19) pandemic; however, nationwide data on COVID-19 outcomes stratified by race/ethnicity and adjusted for clinical characteristics are sparse. This study analyzed the impacts of race/ethnicity on outcomes among US patients with COVID-19.

methodsThis was a retrospective observational study of patients with a confirmed COVID-19 diagnosis in the electronic health record from 01 February 2020 through 14 September 2020. Index encounter site, hospitalization, and mortality were assessed by race/ethnicity (Hispanic, non-Hispanic Black [Black], non-Hispanic White [White], non-Hispanic Asian [Asian], or Other/unknown). Associations between racial/ethnic categories and study outcomes adjusted for patient characteristics were evaluated using logistic regression.

findingsAmong 202,908 patients with confirmed COVID-19, patients from racial/ethnic minority groups were more likely than White patients to be hospitalized on initial presentation (Hispanic: adjusted odds ratio 1·690, 95% CI 1·620-1·763; Black: 1·810, 1·743-1·880; Asian: 1·503, 1·381-1·636) and during follow-up (Hispanic: 1·700, 1·638-1·764; Black: 1·578, 1·526-1·633; Asian: 1·391, 1·288-1·501). Among hospitalized patients, adjusted mortality risk was lower for Black patients (0·881, 0·809-0·959) but higher for Asian patients (1·205, 1·000-1·452).

interpretationRacial/ethnic minority patients with COVID-19 had more severe disease on initial presentation than White patients. Increased mortality risk was attenuated by hospitalization among Black patients but not Asian patients, indicating that outcome disparities may be mediated by distinct factors for different groups. In addition to enacting policies to facilitate equitable access to COVID-19-related care, further analyses of disaggregated population-level COVID-19 data are needed.

Indexed as

COVID-19Electronic Health RecordsEthnic GroupsMinority GroupsRetrospective StudiesSARS-CoV-2United States

Identifiers

PMID34493997
PMCPMC8413267
OpenAlexW3198241158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.