Evidence map›Paper›PMID 34493839›Full record

ArticleProstate cancer and prostatic diseases2023

Hospital volume and outcomes after radical prostatectomy: a national population-based study using patient-reported urinary continence and sexual function.

Julie Nossiter, Melanie Morris, Thomas E Cowling, Matthew G Parry, Arunan Sujenthiran, Ajay Aggarwal, Heather Payne, Jan van der Meulen, Noel W Clarke, Paul Cathcart

Abstract read
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In one paragraph

Article in Prostate cancer and prostatic diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Julie NossiterDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK. jnossiter@rcseng.ac.uk.ORCID 0000-0002-8597-7624
Melanie MorrisDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Thomas E CowlingDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Matthew G ParryDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-9695-6052
Arunan SujenthiranClinical Effectiveness Unit, Royal College of Surgeons of England, London, UK.
Ajay AggarwalDepartment of Radiotherapy, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Heather PayneDepartment of Oncology, University College London Hospitals NHS FoundatIon Trust, London, UK.
Jan van der MeulenDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-9451-2335
Noel W ClarkeDepartment of Urology, The Christie and Salford Royal NHS Foundation Trusts, Salford, UK.
Paul CathcartDepartment of Urology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Royal College of Surgeons of England · GBGuy's and St Thomas' NHS Foundation Trust · GBKing's College London · GBLondon School of Hygiene & Tropical Medicine · GBSalford Royal NHS Foundation Trust · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

Department of Health ACF-2014-20-002Medical Research Council MR/S020470/1
6 · The paper itself

Abstract

backgroundImprovements in short-term outcomes have been reported for hospitals with higher radical prostatectomy (RP) volumes. However, the association with longer-term functional outcomes is unknown.

methodsAll patients diagnosed with non-metastatic prostate cancer in the English NHS between 2014 and 2016 who underwent RP (N = 10,089) were mailed a survey ≥18 months after diagnosis. Differences in patient-reported urinary continence and sexual function (EPIC-26 on scale from 0 to 100) by hospital volume group (≤60, 61-100, 101-140, >140 RPs/year) were estimated using multilevel linear regression.

resultsOverall, 7702 men (76.3%) responded. There were no statistically significant differences in urinary continence (p = 0.08) or sexual function scores with increasing volume group (p = 0.2). When modelled as a linear function, we found a non-significant increase of 0.70 (95% CI -0.41 to 1.80; p = 0.22) in urinary continence and a significant increase of 1.54 (0.62-2.45; p = 0.001) in sexual function scores for a 100-procedure increase in hospital volume, which did not meet the threshold for a minimal clinically important difference (10-12 points). The results were similar for robotic-assisted RP (5529 men [71.8%]).

conclusionsThese results do not support further centralisation of RP services beyond levels in England where four in five hospitals perform >60 RPs/year.

Indexed as

Prostatic NeoplasmsHospitalsHumansMalePatient Reported Outcome MeasuresProstatectomyState Medicine

Identifiers

PMID34493839
OpenAlexW3197685840

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.