ArticleJournal of occupational medicine and toxicology (London, England)2021
The pupillary light reflex (PLR) as a marker for the ability to work or drive - a feasibility study.
Article in Journal of occupational medicine and toxicology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Autonomic Nervous System, Cognition, and Emotional Valence During Different Phases of the Menstrual Cycle-A Narrative Review.NeuroSci · 2025Review
- Multiple factors contribute to pupillary light reflex: implications for screening of traumatic brain injury in military service members.Clinical neurophysiology practice · 2025Article
- Smartphone-Based Pupillometry Using Machine Learning for the Diagnosis of Sports-Related Concussion.Diagnostics (Basel, Switzerland) · 2024Article
- Measuring the Pupillary Light Reflex Using Portable Instruments in Applied Settings.Vision (Basel, Switzerland) · 2024Article
- Pain-induced effects on the pupillary light response under high and low illumination conditions.Frontiers in neurology · 2024Article
- The impact of Alzheimer's disease risk factors on the pupillary light response.Frontiers in neuroscience · 2023Review
- Eye Movements in Mild Traumatic Brain Injury: Ocular Biomarkers.Journal of eye movement research · 2022Article
- Early phase of pupil dilation is mediated by the peripheral parasympathetic pathway.Journal of neurophysiology · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe PLR (pupillary light reflex) can be a marker for pathological medical conditions, such as neurodegenerative or mental health disorders and diseases as well as marker for physiological alterations, such as age, sex or iris color. PLR alterations have been described in people after alcohol consumption, as well. However, the effect of sleep deprivation on PLR parameters is still under debate.
methodsThe aim of this study was to investigate the feasibility of PLR measurements in sleep-deprived and alcohol-exposed participants. In addition, we wanted to identify PLR parameters that were altered by sleep deprivation and alcohol exposure.
resultsAltogether n = 50 participants have been included in this study. Differences in the PLR parameters initial diameter (d
conclusionOur study delivers first promising results to further develop devices that may identify conditions that impair the ability to work or drive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.