Evidence map›Paper›PMID 34493166›Full record

ArticlePharmaceutical biology2021

Khuzaidatul Azidah Ahmad Nazri, Qodriyah Haji Mohd Saad, Norsyahida Mohd Fauzi, Fhataheya Buang, Ibrahim Jantan, Zakiah Jubri

Open access · goldAbstract readComparative Study
In one paragraph

Article in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Khuzaidatul Azidah Ahmad NazriDepartment of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia.ORCID 0000-0001-5992-5428
Qodriyah Haji Mohd SaadDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia.
Norsyahida Mohd FauziDrug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Fhataheya BuangDrug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Ibrahim JantanInstitute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, UKM Bangi, Bangi, Malaysia.
Zakiah JubriDepartment of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia.
National University of Malaysia · MYUniversity Kebangsaan Malaysia Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveThis study sought to determine whether MATERIALS AND

methodsForty-eight female Sprague-Dawley rats were randomly divided into sham [non-ovariectomized; grouped as control, GP extracts (250 and 500 mg/kg), atorvastatin (ATV, 10 mg/kg)] and postmenopausal (PM) groups [ovariectomized rats fed with 5HPO; grouped as PM, GP extracts (250 and 500 mg/kg) and ATV (10 mg/kg)]. Each group (

resultsIn comparison with the untreated PM group, 250 and 500 mg/kg GP supplementation to PM groups reduced the systolic blood pressure (103 ± 2.7, 86 ± 2.4 vs. 156 ± 7.83 mmHg,

conclusionsGP extract might improve vascular dysfunction by suppressing the inflammatory response, consequently preventing blood pressure elevation.

Indexed as

PostmenopauseAnimalsAnti-Inflammatory AgentsAsteraceaeAtorvastatinBlood PressureCarotid Intima-Media ThicknessDiet, High-FatDisease Models, AnimalDose-Response Relationship, DrugEthanolFemaleInflammationPlant ExtractsRatsRats, Sprague-DawleyAnti-Inflammatory AgentsAtorvastatinEthanolPlant ExtractsBlood pressurecholesterolC-reactive proteininterleukin-6ovariectomizedtumour necrosis factor-alphavasoconstrictionvasorelaxation

Identifiers

PMID34493166
PMCPMC8428271
OpenAlexW3197361334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.