Evidence map›Paper›PMID 34492149›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2021

The impact of age and 24-h blood pressure on arterial health in acute ischemic stroke patients: The Norwegian stroke in the young study.

Sahrai Saeed, Ulrike Waje-Andreassen, Halvor Naess, Annette Fromm, Peter M Nilsson

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Vascular phenotypes in early hypertension.Journal of human hypertension · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sahrai SaeedDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Ulrike Waje-AndreassenDepartment of Neurology, Haukeland University Hospital, Bergen, Norway.
Halvor NaessDepartment of Neurology, Haukeland University Hospital, Bergen, Norway.
Annette FrommDepartment of Neurology, Haukeland University Hospital, Bergen, Norway.
Peter M NilssonDepartment of Clinical Sciences, Lund University, Skane University Hospital, Malmö, Sweden.
Haukeland University Hospital · NOSkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of age and 24-h ambulatory blood pressure (ABPM) on arterial stiffness and carotid intima-media thickness (cIMT) in ischemic stroke patients younger than 60 years of age is poorly explored. A total of 385 acute ischemic stroke patients (aged 49.6±9.7 years, 68% men) were prospectively included and grouped in younger (15-44 years, n = 93) and middle-aged (45-60 years, n = 292). Arterial stiffness was measured by carotid-femoral pulse wave velocity (PWV), and cIMT by carotid ultrasound. 24-h ABPM was recorded. The middle-aged stroke patients had higher prevalence of smoking, hypertension, diabetes mellitus, metabolic syndrome and hypercholesterolemia, and had higher PWV and cIMT (all p < .05). In multivariable linear regression analyses adjusted for sex, BMI, smoking, diabetes mellitus, total cholesterol, high-density lipoprotein cholesterol, triglycerides, eGFR, systolic BP and concomitant antihypertensive treatment, 1SD (4.4 years) higher age was associated with higher PWV (β = 0.44,R

Indexed as

Brain IschemiaHypertensionIschemic StrokeStrokeVascular StiffnessAdolescentAdultBlood PressureBlood Pressure Monitoring, AmbulatoryCarotid ArteriesCarotid Intima-Media ThicknessFemaleHumansMaleMiddle AgedPulse Wave Analysisageambulatory blood pressurearterial stiffnesscarotid intima-media thicknesshypertensionischemic strokepulse pressurepulse wave velocity

Identifiers

PMID34492149
PMCPMC8678672
OpenAlexW3197400376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.