Evidence map›Paper›PMID 34491888›Full record

ArticleHuman vaccines & immunotherapeutics2021

Analysis of the adverse events following immunization with inactivated quadrivalent influenza vaccine from 2018 to 2020 in Zhejiang province, with a comparison to trivalent influenza vaccine.

Huakun Lv, Xuejiao Pan, Hui Liang, Ying Wang, Yu Hu

Open access · greenAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huakun LvInstitute Of Immunization And Prevention, Zhejiang Center For Disease Control And Prevention, Hangzhou, Zhejiang, China.
Xuejiao PanInstitute Of Immunization And Prevention, Zhejiang Center For Disease Control And Prevention, Hangzhou, Zhejiang, China.
Hui LiangInstitute Of Immunization And Prevention, Zhejiang Center For Disease Control And Prevention, Hangzhou, Zhejiang, China.
Ying WangInstitute Of Immunization And Prevention, Zhejiang Center For Disease Control And Prevention, Hangzhou, Zhejiang, China.
Yu HuInstitute Of Immunization And Prevention, Zhejiang Center For Disease Control And Prevention, Hangzhou, Zhejiang, China.
Zhejiang Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo summarize reports to the national adverse event following immunization surveillance system (NAEFISS) following inactivated quadrivalent influenza vaccine (QIV) in Zhejiang province from 2018 to 2020.

methodsWe analyzed adverse events following immunization (AEFI) reports following QIV, with a comparison, with the AEFI reports following inactivated trivalent influenza vaccine (TIV). Reporting rates of AEFI were calculated by age, severity of AEFI, categories of AEFI, and reaction categories. The data mining algorithm used in this study was reporting odds ratio (ROR). A value of ROR‑1.96SE >1 (standard error [SE]) was considered as positive signal. These reporting rates between vaccine types were compared through chi-square tests.

resultsNAEFISS received 514 AEFI reports following QIV and 536 reports following TIV, with a reporting rate of 13.66/100,000 100,000 doses/100,000 doses (

conclusionThe present analysis did not identify any new/unexpected safety concerns. We suggested that NAEFISS continue to monitor the safety of QIV.

Indexed as

Influenza, HumanInfluenza VaccinesAdolescentChildChild, PreschoolHumansImmunizationVaccinationVaccines, InactivatedInfluenza VaccinesVaccines, InactivatedAdverse events following immunizationinactivated quadrivalent influenza vaccineinactivated trivalent influenza vaccinesurveillancevaccination

Identifiers

PMID34491888
PMCPMC8828122
OpenAlexW3198419825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.