SynthesisOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2022
Management of Flap Failure After Head and Neck Reconstruction: A Systematic Review and Meta-analysis.
Synthesis in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- A retrospective analysis for the management of oromaxillofacial invasive mucormycosis and systematic literature review.BMC oral health · 2023Pooled it
- Salvage surgery for free flap failure in the maxillofacial region: a comprehensive review of principles and outcomes.Annals of medicine and surgery (2012) · 2026Article
- Second or subsequent microvascular free flaps in head and neck reconstructive surgery: a narrative review.Annals of medicine and surgery (2012) · 2026Article
- Perioperative Predictors of Complications and Flap Loss in Microvascular Reconstructive Surgery: The Role of Fluid Balance, Crystalloid Administration and Operative Time.Journal of clinical medicine · 2026Article
- Free fibula flap for secondary mandibular reconstruction after gunshot injuries in Tigray, northern Ethiopia : A 5-year review of microsurgical challenges and outcomes in a war zone.Wiener klinische Wochenschrift · 2026Article
- Article
- Preventing Free Flap Complications: Key Factors to Keep in Mind.Journal of surgical oncology · 2025Article
- Article
- Extremity and Mandibular Reconstruction After Gunshot Trauma-Orthoplastic Strategies from Five Years of Humanitarian Missions in a Resource-Limited Setting.Journal of clinical medicine · 2025Article
- Twenty Years of "Occasional" Reconstructive Microsurgery: A Retrospective Review of a Single Surgeon's Experience.Plastic and reconstructive surgery. Global open · 2025Article
- Comprehensive analysis of risk factors for flap necrosis in free flap reconstruction of postoperative tissue defects in oral and maxillofacial tumors.Scientific reports · 2024Article
- Management of a Partially Treated Case of Chronic Osteomyelitis of the Hard Palate and Maxillary Sinus.Cureus · 2024Article
- Maxillofacial Microvascular Free-Flap Reconstructions in Pediatric and Young Adult Patients-Outcomes and Potential Factors Influencing Success Rate.Journal of clinical medicine · 2024Article
- Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) Score as a Predictive Model for the Success of Reconstruction of Head and Neck Defects with Free Microvascular Flaps.Journal of clinical medicine · 2023Article
- Postoperative recovery among head and neck cancer patients receiving microvascular free flap surgery with implementing nurse-protocolized targeted sedation: relationship of use of sedatives and mechanical ventilation to length of ICU stay.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- External tissue expansion to salvage failed scalp and forehead reconstruction: a case report.Case reports in plastic surgery & hand surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo systematically review management of flap loss in head and neck construction with free tissue transfer as compared with locoregional flap or conservative management. DATA SOURCES: Medline, Embase, Scopus, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and ClinicalTrials.gov were searched up to October 2019. REVIEW
methodsCandidate articles were independently reviewed by 2 authors. Articles were considered eligible if they included adequate reporting of flap management after flap loss and outcomes for survival of reconstruction, length of hospitalization, and perioperative complications.
resultsA total of 429 patients had acute flap failure in the perioperative period. The overall success with a secondary free flap was 93% (95% CI, 0.89-0.97; n = 26 studies,
conclusionSalvage reconstruction with free tissue transfer has a high success rate. Second free flaps following flap failure had a similar length of hospitalization and lower overall complication rate than locoregional reconstruction or conservative management. A second free tissue transfer, when feasible, is likely a more reliable and effective procedure for salvage reconstruction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.