Evidence map›Paper›PMID 34491798›Full record

ArticleJournal of bacteriology2021

Identification of a Region in Shigella flexneri WzyB Disrupting the Interaction with Wzz

Vincenzo Leo, Min Yan Teh, Elizabeth N H Tran, Renato Morona

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vincenzo LeoDepartment of Molecular and Biomedical Science, Research Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaidegrid.1010.0, Adelaide, South Australia, Australia.ORCID 0000-0002-2903-3004
Min Yan TehDepartment of Molecular and Biomedical Science, Research Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaidegrid.1010.0, Adelaide, South Australia, Australia.
Elizabeth N H TranDepartment of Molecular and Biomedical Science, Research Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaidegrid.1010.0, Adelaide, South Australia, Australia.
Renato MoronaDepartment of Molecular and Biomedical Science, Research Centre for Infectious Diseases, School of Biological Sciences, The University of Adelaidegrid.1010.0, Adelaide, South Australia, Australia.ORCID 0000-0001-7009-7440
The University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shigella flexneri can synthesize polysaccharide chains having complex sugars and a regulated number of repeating units. S. flexneri lipopolysaccharide O antigen (Oag) is synthesized by the Wzy-dependent pathway, which is the most common pathway used in bacteria for polysaccharide synthesis. The inner membrane protein WzyB polymerizes the Oag repeat units into chains, while the polysaccharide copolymerases WzzB and Wzz

Indexed as

Bacterial ProteinsDNA, BacterialGene Expression Regulation, BacterialMutagenesisMutationPlasmidsShigella flexneriBacterial ProteinsDNA, BacteriallipopolysaccharideLPSO antigenShigella flexneriWzyBWzy-dependent pathwayWzzpHS2

Identifiers

PMID34491798
PMCPMC8544411
OpenAlexW3197990861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.