Evidence map›Paper›PMID 34491722›Full record

ArticleACS sensors2021

DNA-Based Smart Reagent for Detecting Alzheimer's Associated MicroRNAs.

Arun Richard Chandrasekaran, Ken Halvorsen

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Aptamer-based DNA nanoswitches for multiplexed protein detection.Chemical communications (Cambridge, England) · 2026
    Article
  3. Article
  4. Aptamer-based DNA nanoswitches for multiplexed protein detection.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Review
  7. Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Arun Richard ChandrasekaranThe RNA Institute, University of Albany, State University of New York, Albany, New York 12222, United States.ORCID 0000-0001-6757-5464
Ken HalvorsenThe RNA Institute, University of Albany, State University of New York, Albany, New York 12222, United States.ORCID 0000-0002-2578-1339
Albany State University · US

Funding

Manipulating nucleic acids: applications in RNA biosensing, single-molecule analysis, and DNA nanotechnologyR35GM124720 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI Ken A Halvorsen · 2017 to 2026
$4.6M
NIGMS NIH HHS R35 GM124720
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disorder, with significant research efforts devoted to identifying new biomarkers for clinical diagnosis and treatment. MicroRNAs have emerged as likely disease regulators and biomarkers for AD, now implicated as having roles in several biological processes related to progression of the disease. In this work, we use the

Indexed as

Alzheimer DiseaseMicroRNAsDNAHumansIndicators and ReagentsDNAIndicators and ReagentsMicroRNAsAlzheimer’s diseasebiomarkersdiagnosticsDNA nanoswitchDNA nanotechnologymicroRNAsneurological disorders

Identifiers

PMID34491722
PMCPMC9404293
OpenAlexW3196690476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.