Evidence map›Paper›PMID 34491476›Full record

ArticleJapanese journal of ophthalmology2021

Assessment of the anterior scleral thickness in central serous chorioretinopathy patients by optical coherence tomography.

José Ignacio Fernández-Vigo, Francisco Javier Moreno-Morillo, Hang Shi, Fernando Ly-Yang, Bárbara Burgos-Blasco, Noemí Güemes-Villahoz, Juan Donate-López, Julián García-Feijóo

Abstract read
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In one paragraph

Article in Japanese journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Linking increased anterior scleral thickness, pachychoroid, and macular microvascular changes in chronic central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  2. Review
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  4. Article
  5. Pachychoroid disease: review and update.Eye (London, England) · 2025
    Review
  6. Article
  7. Review
  8. Biomechanical properties measured with dynamic Scheimpflug analyzer in central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  9. Review
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  12. Article
  13. Pathomechanisms in central serous chorioretinopathy: A recent update.International journal of retina and vitreous · 2023
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

José Ignacio Fernández-VigoDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain. jfvigo@hotmail.com.ORCID http://orcid.org/0000-0001-8745-3464
Francisco Javier Moreno-MorilloDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Hang ShiDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Fernando Ly-YangDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Bárbara Burgos-BlascoDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Noemí Güemes-VillahozDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Juan Donate-LópezDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Julián García-FeijóoDepartment of Ophthalmology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Professor Martin Lagos s/n, 28040, Madrid, Spain.
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESUniversidad Complutense de Madrid · ESUniversidad Internacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the anterior scleral thickness (AST) and describe the presence of a visible supraciliary space (SCS) in central serous chorioretinopathy (CSC) patients by swept-source optical coherence tomography (SS-OCT). STUDY

designCross-sectional comparative study. MATERIAL AND

methodsThree groups were studied: 1) 64 eyes of 54 patients with CSC with persistent subretinal fluid (SRF); 2) 42 fellow eyes of CSC patients without SRF; 3) 65 eyes of 65 controls matched by age, sex and axial length (AL). The AST was measured in the temporal and nasal quadrants at 0, 1, and 2 mm from the scleral spur by SS-OCT. The presence of a visible SCS was also assessed.

resultsNo differences were observed in the AST0 among the three groups (p≥ 0.665). The temporal AST1 was significantly thicker in the CSC group (530.3 ±67.1 µm) than in the controls (505.5 ±73.9; p=0.041). Mean AST2 was also thicker in the CSC group and the fellow eyes both for the temporal (519.4 ±89.1 µm and 519.8 ±98.5 µm respectively) and nasal quadrants (564.2 ±124.9 µm and 570.5 ±131.0 µm) than in the controls (450.1 ±76.8 and 473.3 ±111.6 µm) (all p≤0.001). A visible SCS was detected in the eyes of 8 CSC patients, in 4 fellow eyes and only in 1 control eye.

conclusionsAST measured by SS-OCT was significantly greater in CSC eyes than in healthy eyes. Also, a visible SCS was detected in CSC eyes. Thus, thicker sclera in CSC eyes could be associated with the physiopathology of this disease.

Indexed as

Central Serous ChorioretinopathyTomography, Optical CoherenceChoroidCross-Sectional StudiesFluorescein AngiographyHumansScleraAnterior scleral thicknessCentral serous chorioretinopathyOptical coherence tomographyScleraSupraciliary space

Identifiers

PMID34491476
OpenAlexW3198534824

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.