Evidence map›Paper›PMID 34491468›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2021

Female sexual dysfunction in multiple system atrophy: a prospective cohort study.

Cecilia Raccagni, Elisabetta Indelicato, Victoria Sidoroff, Martin Daniaux, Angelika Bader, Bettina Toth, Lukas A Jelisejevas, Margarethe Hochleitner, Alessandra Fanciulli, Fabian Leys and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Sex-related differences in the clinical presentation of multiple system atrophy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Female sexual dysfunction in multiple system atrophy: does it matter?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Cecilia RaccagniDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Elisabetta IndelicatoDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. elisabetta.indelicato@i-med.ac.at.ORCID 0000-0003-0217-8630
Victoria SidoroffDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Martin DaniauxDepartment of Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Angelika BaderGender Medicine and Diversity Unit, Medical University of Innsbruck, Innrain 66, 6020, Innsbruck, Austria.
Bettina TothDepartment of Gynecological Endocrinology and Reproductive Medicine, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Lukas A JelisejevasDepartment of Urology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Margarethe HochleitnerGender Medicine and Diversity Unit, Medical University of Innsbruck, Innrain 66, 6020, Innsbruck, Austria.
Alessandra FanciulliDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Fabian LeysDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Sabine EschlboeckDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Christine KaindlstorferDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Sylvia BoeschDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Gregor K WenningDepartment of Neurology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Innsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe diagnosis of probable multiple system atrophy relies on the presence of severe cardiovascular or urogenital autonomic failure. Erectile dysfunction is required to fulfil the latter criterion in men, whereas no corresponding item is established for women. In this study, we aimed to investigate sexual dysfunction in women with multiple system atrophy.

methodsWe administered the Female Sexual Function Index questionnaire and interviewed women with multiple system atrophy and age-matched controls regarding the presence of "genital hyposensitivity."

resultsWe recruited 25 women with multiple system atrophy and 42 controls. Female Sexual Function Index scores in sexually active women with multiple system atrophy were significantly lower (multiple system atrophy = 10; 15.4, 95% CI [10.1, 22.1], controls = 37; 26.1 [24.1, 28.1], p = 0.0004). The lowest scores concerned the domains of desire, arousal and lubrication. Genital hyposensitivity was reported by 56% of the patients with multiple system atrophy and 9% controls (p < 0.0001).

conclusionsSexual dysfunction is highly prevalent in women with multiple system atrophy. Screening for disturbances in specific sexual domains should be implemented in the clinical evaluation of women with suggestive motor symptoms.

Indexed as

Erectile DysfunctionMultiple System AtrophySexual Dysfunction, PhysiologicalFemaleHumansMaleProspective StudiesSexual BehaviorSurveys and QuestionnairesArousalAutonomic failureFemaleLubricationMultiple system atrophyNon-motor symptomsSexual dysfunction

Identifiers

PMID34491468
PMCPMC8629866
OpenAlexW3198747498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.