Evidence map›Paper›PMID 34491140›Full record

ArticleAutophagy2022

Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile.

Heidemarie Rossiter, Dragan Copic, Martin Direder, Florian Gruber, Samuele Zoratto, Martina Marchetti-Deschmann, Christopher Kremslehner, Michaela Sochorová, Ionela-Mariana Nagelreiter, Veronika Mlitz and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Infection withAnimals : an open access journal from MDPI · 2023
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Heidemarie RossiterDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0616-6592
Dragan CopicLaboratory for Cardiac and Thoracic Diagnosis, Regeneration and Applied Immunology, Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Martin DirederLaboratory for Cardiac and Thoracic Diagnosis, Regeneration and Applied Immunology, Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Florian GruberDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-1094-5641
Samuele ZorattoInstitute of Chemical Technologies and Analytics, Technical University of Vienna, Vienna, Austria.
Martina Marchetti-DeschmannInstitute of Chemical Technologies and Analytics, Technical University of Vienna, Vienna, Austria.
Christopher KremslehnerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Michaela SochorováDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Ionela-Mariana NagelreiterDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Veronika MlitzDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Maria BuchbergerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Barbara LengauerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Bahar GolabiDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Supawadee SuksereeDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-7011-9352
Michael MildnerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
Leopold EckhartDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-5645-2036
Erwin TschachlerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0248-1798
Medical University of Vienna · ATUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abbreviationsATG7: autophagy related 7; BODIPY: boron dipyrromethene; DAG: diacyl glycerides; DBI: diazepam binding inhibitor; GFP: green fluorescent protein; KRT14: keratin 14; HPLC-MS: high performance liquid chromatography-mass spectrometry; LD: lipid droplet; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; MSI: mass spectrometric imaging; ORO: Oil Red O; PC: phosphatidylcholine; PE: phosphatidylethanolamine; PG: preputial gland; PLIN2: perilipin 2; PtdIns: phosphatidylinositol; PL: phospholipids; POPC: 1-palmitoyl-2-oleoyl-PC; PS: phosphatidylserine; qRT-PCR: quantitative reverse transcribed PCR; SG: sebaceous gland; scRNAseq: single-cell RNA sequencing; TAG: triacylglycerides; TLC: thin layer chromatography.

Indexed as

Aging, PrematureSebumAnimalsAutophagyMicePerilipin-2PheromonesPhosphatidylserinesPhospholipidsPerilipin-2PheromonesPhosphatidylserinesPhospholipidsAutophagosomesGFP-LC3lipid dropletsperilipinsebocytes

Identifiers

PMID34491140
PMCPMC9196838
OpenAlexW3198368059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.