ArticleEnvironmental microbiology2021
Solid diet manipulates rumen epithelial microbiota and its interactions with host transcriptomic in young ruminants.
Article in Environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 57 citations in OpenAlex.
- Age-driven shifts of the camel gut microbiome and resistome in extensively reared dromedary camels.Microbiology spectrum · 2026Article
- Bidirectional regulation of gut microbiota and young ruminant host: implications for intestinal development and mucosal immunity.Journal of animal science and biotechnology · 2026Review
- Early supplemental feeding improves post-weaning growth restriction in lambs via the gastrointestinal-metabolic axis.Applied and environmental microbiology · 2026Article
- Review
- Elucidating the pathogenesis of rumen abnormal adipose deposition in high-concentrate fed Hu sheep through transcriptomic profiling.BMC veterinary research · 2025Article
- Effects of Fermentation and Enzymatic Hydrolysis of Cottonseed Protein on Rumen Fermentation Characteristics, Intestinal Barrier Function, and Hepatic Metabolism in Suckling Lambs.Animals : an open access journal from MDPI · 2025Article
- Pasteurized Colostrum Improves Blood Immunity and Gastrointestinal Microbiota in Dairy Calves from Birth to 180 Days of Age.Microorganisms · 2025Article
- Wheat straw and alfalfa hay alone or combined in a high-concentrate diet alters microbial-host interaction in the rumen of lambs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism.Microbiome · 2025Article
- Effect of Dietary Supplementation ofAnimals : an open access journal from MDPI · 2025Article
- Effects of starter diets with different neutral detergent fiber levels on gastrointestinal tract development, microbial profiles, nutrient digestibility, and growth performance in Xinong Saanen dairy goat kids.Journal of animal science · 2025Article
- Recent nutritional strategies and feed additives to stimulate proper rumen development in young goats.Translational animal science · 2025Article
- Feeding systems influence the rumen resistome in yaks by changing the microbiome.Frontiers in microbiology · 2025Article
- Discrepancies in the rumen microbiome, metabolome, and serum metabolome among Hu sheep, East Friesian sheep, and East Friesian × Hu crossbred sheep.Frontiers in microbiology · 2025Article
- Butyrate metabolism in rumen epithelium affected by host and diet regime through regulating microbiota in a goat model.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Interactions between rumen epithelium-associated microbiota and host immunological and metabolic adaptations in response to different milk replacer feeding intensities in dairy calves.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Multiomics of yaks reveals significant contribution of microbiome into host metabolism.NPJ biofilms and microbiomes · 2024Article
- Maternal gastrointestinal microbiome shapes gut microbial function and resistome of newborns in a cow-to-calf model.Microbiome · 2024Article
- Does Pelleted Starter Feed Restriction and Provision of Total Mixed Ration Ad Libitum during Weaning Influence the Behavior of Dairy Calves?Animals : an open access journal from MDPI · 2024Article
- The Bifidobacterium-dominated fecal microbiome in dairy calves shapes the characteristic growth phenotype of host.NPJ biofilms and microbiomes · 2024Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solid diet supplementation in the early life stages of ruminants could improve rumen microbiota and tissue development. However, most studies focus on bacteria in the rumen content community. The microbiota attached on rumen epithelium are rarely investigated, and their correlations with rumen content bacteria and host transcripts are unknown. In this study, rumen digesta attached in the epithelium from goats in three diet regimes (milk replacer only, milk replacer supplemented concentrate and milk replacer supplemented concentrate plus alfalfa pellets) were collected for measurement of the epithelial microbiota using next generation sequencing. Correspondingly, the rumen tissues of the same animals were measured with the host transcriptome. The distinct microbial structures and compositions between rumen content and epithelial communities were associated with solid diet supplementation. Regarding rumen development in pre-weaning ruminants, a solid diet, especially its accompanying neutral detergent fibre nutrients, was the most significant driver that influenced the rumen microbiota and epithelium gene expression. Compared with content bacteria, rumen epithelial microbiota had a stronger association with the host transcriptome. The host transcriptome correlated with host phenotypes were associated with rumen epithelial microbiota and solid diet. This study reveals that the epithelial microbiota is crucial for proper rumen development, and solid diet could improve rumen development through both the rumen content and epithelial microbiota.
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