Evidence map›Paper›PMID 34490802›Full record

ArticleTechnology in cancer research & treatment

Clinically Oriented Target Contour Evaluation Using Geometric and Dosimetric Indices Based on Simple Geometric Transformations.

Lixun Xian, Guangjun Li, Qing Xiao, Zhibin Li, Xiangbin Zhang, Li Chen, Zhenyao Hu, Sen Bai

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Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lixun XianDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Guangjun LiDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.ORCID 0000-0003-2054-1771
Qing XiaoDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhibin LiDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xiangbin ZhangDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Li ChenDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhenyao HuDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Sen BaiDepartment of Radiation Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn radiotherapy, geometric indices are often used to evaluate the accuracy of contouring. However, the ability of geometric indices to identify the error of contouring results is limited primarily because they do not consider the clinical background. The purpose of this study is to investigate the relationship between geometric and clinical dosimetric indices.

methodsFour different types of targets were selected (C-shaped target, oropharyngeal cancer, metastatic spine cancer, and prostate cancer), and the translation, scaling, rotation, and sine function transformation were performed with the software Python to introduce systematic and random errors. The transformed contours were regarded as reference contours. Dosimetric indices were obtained from the original dose distribution of the radiotherapy plan. The correlations between geometric and dosimetric indices were quantified by linear regression.

resultsThe correlations between the geometric and dosimetric indices were inconsistent. For systematic errors, and with the exception of the sine function transformation (R

conclusionsClinically, an assessment of the contour accuracy of the region-of-interest is not feasible based on geometric indices alone. Dosimetric indices should be added to the evaluations of the accuracy of the delineation results, which can be helpful for explaining the clinical dose response relationship of delineation more comprehensively and accurately.

Indexed as

Data AnalysisDiagnostic ImagingHumansNeoplasmsOrgans at RiskRadiation OncologyRadiometryRadiotherapy DosageRadiotherapy, Image-GuidedRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-Assistedcontour evaluationdosimetric indicesgeometric indicesgeometric transformationtarget volume

Identifiers

PMID34490802
PMCPMC8427914

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.