Evidence map›Paper›PMID 34490781›Full record

ArticleACS nano2021

Grant A Knappe, Eike-Christian Wamhoff, Benjamin J Read, Darrell J Irvine, Mark Bathe

Abstract read
In one paragraph

Article in ACS nano, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Nano-Bio Interactions between DNA Nanocages and Human Serum Albumin.Journal of chemical theory and computation · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Aptamers as promising nanotheranostic tools in the COVID-19 pandemic era.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grant A KnappeDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Eike-Christian WamhoffDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-8665-5512
Benjamin J ReadKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Darrell J IrvineDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-8637-1405
Mark BatheDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.ORCID 0000-0002-6199-6855

Funding

Identification of neutralizing epitopes on SARS-CoV-2 spike for design of vaccines and small-molecule antiviralsUM1AI144462 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BURTON, DENNIS R. · 2019 to 2025
$201.6M
TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YAFFE, MICHAEL B · 1985 to 2020
$25.6M
Simultaneous profiling of neuronal synapse activities, proteins, and messenger RNAs at the single-cell levelR01MH112694 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Mark Bathe · 2017 to 2026
$2.8M
Investigation of Synthetic DNA-based Viral Particles for Spatially Controlled Antigen PresentationR01AI162307 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Mark Bathe, Facundo Damian Batista · 2021 to 2026
$2.4M
Structured DNA Nanoparticles Therapeutic mRNA and CRISPR/Cas9 DeliveryR21EB026008 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BATHE, MARK · 2018 to 2021
$796k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI162307NIAID NIH HHS UM1 AI144462NIBIB NIH HHS R21 EB026008NIEHS NIH HHS P30 ES002109NIMH NIH HHS R01 MH112694
6 · The paper itself

Abstract

DNA origami is a powerful nanomaterial for biomedical applications due in part to its capacity for programmable, site-specific functionalization. To realize these applications, scalable and efficient conjugation protocols are needed for diverse moieties ranging from small molecules to biomacromolecules. Currently, there are no facile and general methods for

Indexed as

DNANanostructuresNucleic Acid ConformationDNAbioconjugationclick chemistryDNA nanotechnologyDNA origaminanoparticlesreaction characterization

Identifiers

PMID34490781
PMCPMC8628367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.