Evidence map›Paper›PMID 34490586›Full record

ArticlePain and therapy2021

Endoscopic Transforaminal Lumbar Foraminotomy: A Systematic Review and Meta-Analysis.

Enrico Giordan, Domenico Billeci, Jacopo Del Verme, Giustino Varrassi, Flaminia Coluzzi

Open access · goldAbstract read
In one paragraph

Article in Pain and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

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  10. Evolving Role of Lumbar Decompression: A Narrative Review.International journal of spine surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Enrico GiordanDepartment of Neurosurgery, Aulss 2 Marca Trevigiana, Via Piazzale 1, 31100, Treviso, Veneto, Italy. enrico.giordan@aulss2.veneto.it.ORCID http://orcid.org/0000-0002-8863-116X
Domenico BilleciDepartment of Neurosurgery, Aulss 2 Marca Trevigiana, Via Piazzale 1, 31100, Treviso, Veneto, Italy.ORCID http://orcid.org/0000-0002-3218-6685
Jacopo Del VermeDepartment of Neurosurgery, Aulss 2 Marca Trevigiana, Via Piazzale 1, 31100, Treviso, Veneto, Italy.
Giustino VarrassiFondazione Paolo Procacci, Rome, Italy.ORCID http://orcid.org/0000-0002-3822-2923
Flaminia ColuzziDepartment of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino, Latina, Italy.ORCID http://orcid.org/0000-0001-7184-5519
AULSS 2 Marca Trevigiana · ITFondazione Roma · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpinal endoscopic techniques have recently been applied to complex degenerative conditions or failed back surgery syndrome. We performed a systematic review and meta-analysis to assess transforaminal endoscopic lumbar foraminotomy (TELF) outcomes and adverse event rates. We also analyzed the effectiveness of the technique for chronic pain after arthrodesis or previous spinal surgery.

methodsMultiple databases were searched for studies published in the English language, involving patients > 18 years old who underwent endoscopic foraminotomy. Outcomes included the rate of patients who showed "excellent" and "good" postoperative improvement, decreased leg pain, and improved Oswestry Disability Index (ODI) scores. Adverse events considered in the analysis included nerve root damage and intraoperative dural tear, the proportion of patients requiring revision surgery or recurrences, and infections.

resultsA total of 14 studies, encompassing 600 patients, were identified. Approximately 85% of patients improved significantly after TELF, without significant differences among different groups (85% vs. 78%, respectively). Mean leg pain decreased an average of 5.2 points, and ODI scores improved by 41.2%. Patients with previous spine surgery or failed back surgery syndrome had higher postoperative leg dysesthesia rates after TELF (14% vs. 1%, respectively).

conclusionTELF is a useful and safe method to achieve decompression in foraminal stenosis. This technique is indicated in the elderly or patients with comorbidities. Preoperative planning is paramount in determining the foraminal size and endoscope trajectory. A diamond burr is recommended because it has an advantage over the regular endoscopic shaver in bleeding control and complication avoidance.

Indexed as

EndoscopyForaminalForaminotomyLumbarSpineStenosis

Identifiers

PMID34490586
PMCPMC8586101
OpenAlexW3196587066

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.