Evidence map›Paper›PMID 34490299›Full record

SynthesisFrontiers in medicine2021

Risk of Reactivation of Hepatitis B Virus (HBV) and Tuberculosis (TB) and Complications of Hepatitis C Virus (HCV) Following Tocilizumab Therapy: A Systematic Review to Inform Risk Assessment in the COVID-19 Era.

Cori Campbell, Monique I Andersson, M Azim Ansari, Olivia Moswela, Siraj A Misbah, Paul Klenerman, Philippa C Matthews

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Expert views on screening for tuberculosis infection in patients commencing treatment with a biologic agent.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
  8. Review
  9. Methylprednisolone PromotesMicroorganisms · 2023
    Article
  10. Review
  11. Review
  12. COVID-19: Has the Liver Been Spared?International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Navigating past and current hepatitis B infection in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cori CampbellNuffield Department of Medicine, University of Oxford, Medawar Building for Pathogen Research, Oxford, United Kingdom.
Monique I AnderssonDepartment of Infectious Diseases and Microbiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
M Azim AnsariNuffield Department of Medicine, University of Oxford, Medawar Building for Pathogen Research, Oxford, United Kingdom.
Olivia MoswelaPharmacy Department, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
Siraj A MisbahDepartment of Clinical Immunology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
Paul KlenermanNuffield Department of Medicine, University of Oxford, Medawar Building for Pathogen Research, Oxford, United Kingdom.
Philippa C MatthewsNuffield Department of Medicine, University of Oxford, Medawar Building for Pathogen Research, Oxford, United Kingdom.
John Radcliffe Hospital · GBUniversity of Oxford · GBMedawar Building for Pathogen Research · GB

Funding

Wellcome Trust 109965/Z/15/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biologicCOVID-19hepatitis B virusinfectionreactivationSARS-CoV-2tocilizumabtuberculosis

Identifiers

PMID34490299
PMCPMC8417527
OpenAlexW3151579082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.