Evidence map›Paper›PMID 34490289›Full record

SynthesisFrontiers in medicine2021

Binding Potassium to Improve Treatment With Renin-Angiotensin-Aldosterone System Inhibitors: Results From Multiple One-Stage Pairwise and Network Meta-Analyses of Clinical Trials.

Frank Lizaraso-Soto, Eduardo Gutiérrez-Abejón, Juan Bustamante-Munguira, Débora Martín-García, María Montserrat Chimeno, Álvaro Nava-Rebollo, Álvaro Maurtua-Briseño-Meiggs, Darío Fernández-Zoppino, Elena Bustamante-Munguira, Félix Jesús de Paz and 5 more

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Frank Lizaraso-SotoPharmacological Big Data Laboratory, University of Valladolid, Valladolid, Spain.
Eduardo Gutiérrez-AbejónPharmacological Big Data Laboratory, University of Valladolid, Valladolid, Spain.
Juan Bustamante-MunguiraCardiac Surgery Department, University Clinical Hospital of Valladolid, Valladolid, Spain.
Débora Martín-GarcíaClinical Nephrology Unit, University Clinical Hospital of Valladolid, Valladolid, Spain.
María Montserrat ChimenoInternal Medicine Department, Hospital Virgen de la Concha, Zamora, Spain.
Álvaro Nava-RebolloNephrology Department, Hospital Virgen de la Concha, Zamora, Spain.
Álvaro Maurtua-Briseño-MeiggsWoodland Medical Practice-NHS, Lincolnshire, United Kingdom.
Darío Fernández-ZoppinoDepartment of Health Sciences, Faculty of Health Science, University of Burgos, Burgos, Spain.
Elena Bustamante-MunguiraIntensive Care Unit, University Clinical Hospital of Valladolid, Valladolid, Spain.
Félix Jesús de PazPharmacological Big Data Laboratory, University of Valladolid, Valladolid, Spain.
Jesús Grande-VilloriaNephrology Department, Hospital Virgen de la Concha, Zamora, Spain.
Carlos Ochoa-SangradorClinical Epidemiology Support Office, Sanidad de Castilla y León, Zamora, Spain.
Manuel PascualTransplantation Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
F Javier ÁlvarezPharmacological Big Data Laboratory, University of Valladolid, Valladolid, Spain.
Francisco Herrera-GómezPharmacological Big Data Laboratory, University of Valladolid, Valladolid, Spain.
Universidad de Valladolid · ESHospital Virgen de la Concha · ESJunta de Castilla y León · ESUniversidad de Burgos · ESUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This manuscript presents findings from the first dichotomous data pooling analysis on clinical trials (CT) regarding the effectiveness of binding potassium. The results emanated from pairwise and network meta-analyses aiming evaluation of response to commercial potassium-binding polymers, that is, to achieve and maintain normal serum potassium (

Indexed as

hyperkalemiameta-analysis (as topic)mineralocorticoid receptor antagonistsnanomedicinepotassium-binding polymers

Identifiers

PMID34490289
PMCPMC8416895
OpenAlexW3193438815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.