Evidence map›Paper›PMID 34490219›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Hydroxyapatite-Coated Titanium by Micro-Arc Oxidation and Steam-Hydrothermal Treatment Promotes Osseointegration.

Xiaojun Wang, Lina Mei, Xuesheng Jiang, Mingchao Jin, Yan Xu, Jianyou Li, Xiongfeng Li, Zhipeng Meng, Junkun Zhu, Fengfeng Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Antimicrobial Cu-Doped TiOMaterials (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Xiaojun WangDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Lina MeiInternal Medicine, Huzhou Maternity and Child Health Care Hospital, Huzhou, China.
Xuesheng JiangDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Mingchao JinDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Yan XuDepartment of Rehabilitation, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Jianyou LiDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Xiongfeng LiDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Zhipeng MengDepartment of Anaesthesiology, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Junkun ZhuOrthopedics Rehabilitation Department, Lishui Municipal Central Hospital, Lishui, China.
Fengfeng WuDepartment of Orthopedics, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Zhejiang University Huzhou Hospital, Huzhou, China.
Huzhou Central Hospital · CNZhejiang University · CNHuzhou University · CNHuzhou Women and Children's Hospital · CNLishui Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Titanium (Ti)-based alloys are widely used in tissue regeneration with advantages of improved biocompatibility, high mechanical strength, corrosion resistance, and cell attachment. To obtain bioactive bone-implant interfaces with enhanced osteogenic capacity, various methods have been developed to modify the surface physicochemical properties of bio-inert Ti and Ti alloys. Nano-structured hydroxyapatite (HA) formed by micro-arc oxidation (MAO) is a synthetic material, which could facilitate osteoconductivity, osteoinductivity, and angiogenesis on the Ti surface. In this paper, we applied MAO and steam-hydrothermal treatment (SHT) to produce HA-coated Ti, hereafter called Ti-M-H. The surface morphology of Ti-M-H1 was observed by scanning electron microscopy (SEM), and the element composition and the roughness of Ti-M-H1 were analyzed by energy-dispersive X-ray analysis, an X-ray diffractometer (XRD), and Bruker stylus profiler, demonstrating the deposition of nano-HA particles on Ti surfaces that were composed of Ca, P, Ti, and O. Then, the role of Ti-M-H in osteogenesis and angiogenesis

Indexed as

angiogenesismicro-arc oxidationosseointegrationosteogenesisosteoimmune microenvironment

Identifiers

PMID34490219
PMCPMC8417371
OpenAlexW3194682373

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.