Evidence map›Paper›PMID 34490083›Full record

ArticleFrontiers in oncology2021

Identification of Eleven Novel

Yosr Hamdi, Najah Mighri, Maroua Boujemaa, Nesrine Mejri, Sonia Ben Nasr, Mariem Ben Rekaya, Olfa Messaoud, Hanen Bouaziz, Yosra Berrazega, Haifa Rachdi and 15 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  10. Prevalence of Clinically Relevant GermlineFrontiers in genetics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 9 institutions in 1 country.

Yosr HamdiLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Najah MighriLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Maroua BoujemaaLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Nesrine MejriLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Sonia Ben NasrLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Mariem Ben RekayaLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Olfa MessaoudLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Hanen BouazizLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Yosra BerrazegaMedical Oncology Department, Abderrahman Mami Hospital, Faculty of Medicine Tunis, University Tunis El Manar, Tunis, Tunisia.
Haifa RachdiMedical Oncology Department, Abderrahman Mami Hospital, Faculty of Medicine Tunis, University Tunis El Manar, Tunis, Tunisia.
Olfa JaidaneSurgical Oncology Department, Salah Azaiez Institute of Cancer, Tunis, Tunisia.
Nouha DaoudMedical Oncology Department, Abderrahman Mami Hospital, Faculty of Medicine Tunis, University Tunis El Manar, Tunis, Tunisia.
Aref ZribiDepartment of Medical Oncology, Military Hospital of Tunis, Tunis, Tunisia.
Jihene AyariDepartment of Medical Oncology, Military Hospital of Tunis, Tunis, Tunisia.
Houda El BennaLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Soumaya LabidiLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Jamel Ben HassounaSurgical Oncology Department, Salah Azaiez Institute of Cancer, Tunis, Tunisia.
Abderazzek HaddaouiDepartment of Medical Oncology, Military Hospital of Tunis, Tunis, Tunisia.
Khaled RahalSurgical Oncology Department, Salah Azaiez Institute of Cancer, Tunis, Tunisia.
Farouk BennaDepartment of Radiation Oncology, University of Tunis, Tunis, Tunisia.
Ridha MradDepartment of Human Genetics, Charles Nicolle Hospital, Tunis, Tunisia.
Slim Ben AhmedFaculty of Medicine of Sousse Department of Medical Oncology Farhat Hached University Hospital University of Sousse, Sousse, Tunisia.
Hamouda BoussenLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Samir BoubakerLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Sonia AbdelhakLaboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.
Tunis El Manar University · TNMilitary Hospital of Tunis · TNTunis University · TNInstitut Pasteur de Tunis · TNInstitut Salah-Azaïz · TNAbderrahmane Mami Hospital · TNFaculté de médecine de TunisHôpital Charles-Nicolle · TNUniversity of Sousse · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer is the world's most common cancer among women. It is becoming an increasingly urgent problem in low- and middle-income countries (LMICs) where a large fraction of women is diagnosed with advanced-stage disease and have no access to treatment or basic palliative care. About 5-10% of all breast cancers can be attributed to hereditary genetic components and up to 25% of familial cases are due to mutations in

methodsA total of 354 patients diagnosed with breast and ovarian cancers, including 5 male breast cancer cases, have been investigated for

resultsIn the current study, 16 distinct mutations were detected: 10 in

conclusionOur study provides new insights into breast and ovarian cancer genetic landscape in the under-represented North African populations. The prevalence assessment of novel and recurrent

Indexed as

BRCA cancersclinicopathological signaturesgenetic testingnovel BRCA mutationsprecision medicine

Identifiers

PMID34490083
PMCPMC8417726
OpenAlexW3128946400

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.