Evidence map›Paper›PMID 34490042›Full record

ArticleFrontiers in genetics2021

Whole Genome Sequence Data From Captive Baboons Implicate

Mark Z Kos, Melanie A Carless, Lucy Blondell, M Michelle Leland, Koyle D Knape, Harald H H Göring, Charles Ákos Szabó

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Neuroimaging in the Epileptic Baboon.Frontiers in veterinary science · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mark Z KosDepartment of Human Genetics, South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Edinburg, TX, United States.
Melanie A CarlessDepartment of Biology, The University of Texas at San Antonio, San Antonio, TX, United States.
Lucy BlondellDepartment of Human Genetics, South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Edinburg, TX, United States.
M Michelle LelandLaboratory Animal Research, UT Health San Antonio, San Antonio, TX, United States.
Koyle D KnapeDepartment of Neurology, UT Health San Antonio, San Antonio, TX, United States.
Harald H H GöringDepartment of Human Genetics, South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Edinburg, TX, United States.
Charles Ákos SzabóDepartment of Neurology, UT Health San Antonio, San Antonio, TX, United States.
The University of Texas Rio Grande Valley · USThe University of Texas Health Science Center at Houston · USThe University of Texas at San Antonio · USThe University of Texas Health Science Center at San Antonio · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
WNV REPLIVAX VACCINE IN NON-HUMAN PRIMATESP51RR013986 · NCRR · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI GOLDBERG, ERWIN · 1999 to 2011
$79.1M
SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
Baboon Model for Genetics of Human Generalized EpilepsyR01NS047755 · NINDS · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI WILLIAMS, JEFF · 2004 to 2007
$1.1M
EXTRAMURAL RES FACILITIES CONSTRC06RR015456 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 2001 to 2001
$1.1M
Brain MRI and Histopathology of the Epileptic BaboonR21NS084198 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SZABO, CHARLES AKOS · 2014 to 2015
$411k
BABOON F-CAGE FACILITY FOR PRIMATE RESEARCH CENTERC06RR014578 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 1999 to 1999
–
MOLECULAR AND BIOCHEMICAL GENETICS LABORATORY RENOVATIONC06RR013556 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 1998 to 1998
–
NCRR NIH HHS C06 RR013556NCRR NIH HHS C06 RR014578NCRR NIH HHS C06 RR015456NCRR NIH HHS P51 RR013986NIBIB NIH HHS R01 EB015611NIH HHS P51 OD011133NINDS NIH HHS R01 NS047755NINDS NIH HHS R21 NS084198
6 · The paper itself

Abstract

In this study, we investigate the genetic determinants that underlie epilepsy in a captive baboon pedigree and evaluate the potential suitability of this non-human primate model for understanding the genetic etiology of human epilepsy. Archived whole-genome sequence data were analyzed using both a candidate gene approach that targeted variants in baboon homologs of 19 genes (

Indexed as

association testbaboonepilepsygenetic generalized epilepsyidiopathic generalized epilepsyPapioRBFOX1whole-genome sequence

Identifiers

PMID34490042
PMCPMC8417722
OpenAlexW3195940893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.