Evidence map›Paper›PMID 34490028›Full record

ArticleFrontiers in genetics2021

Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System.

Kevin Gley, Frieder Hadlich, Nares Trakooljul, Fiete Haack, Eduard Murani, Ulrike Gimsa, Klaus Wimmers, Siriluck Ponsuksili

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kevin GleyLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Frieder HadlichLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Nares TrakooljulLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Fiete HaackLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Eduard MuraniLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Ulrike GimsaLeibniz Institute for Farm Animal Biology (FBN), Institute of Behavioral Physiology, Dummerstorf, Germany.
Klaus WimmersLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Siriluck PonsuksiliLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Dummerstorf, Germany.
Research Institute for Farm Animal Biology (FBN) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular basis of porcine coping behavior (CB) relies on a sophisticated interplay of genetic and epigenetic features. Deep sequencing technologies allowed the identification of a plethora of new regulatory small non-coding RNA (sncRNA). We characterized mRNA and sncRNA profiles of central parts of the physiological stress response system including amygdala, hippocampus, hypothalamus and adrenal gland using systems biology for integration. Therefore, ten each of high- (HR) and low- (LR) reactive pigs (

Indexed as

coping behaviorHPA axislimbic systemmixomicssncRNAtiRNAtranscriptomicstRF

Identifiers

PMID34490028
PMCPMC8417057
OpenAlexW3193447308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.