Evidence map›Paper›PMID 34489981›Full record

ArticleFrontiers in immunology2021

Amphibian (

Kelsey A Hauser, Julia C Singer, Muhammad Riadul H Hossainey, Tyler E Moore, Emily S Wendel, Amulya Yaparla, Namarta Kalia, Leon Grayfer

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Current issues in molecular biology · 2026
    Review
  3. A perspective into the relationships between amphibian (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  4. The amphibian immune system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kelsey A HauserDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Julia C SingerDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Muhammad Riadul H HossaineyDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Tyler E MooreDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Emily S WendelDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Amulya YaparlaDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Namarta KaliaDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
Leon GrayferDepartment of Biological Sciences, George Washington University, Washington, DC, United States.
George Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global amphibian declines are compounded by ranavirus infections such as Frog Virus 3 (FV3), and amphibian tadpoles more frequently succumb to these pathogens than adult animals. Amphibian gastrointestinal tracts represent a major route of ranavirus entry, and viral pathogenesis often leads to hemorrhaging and necrosis within this tissue. Alas, the differences between tadpole and adult amphibian immune responses to intestinal ranavirus infections remain poorly defined. As interferon (IFN) cytokine responses represent a cornerstone of vertebrate antiviral immunity, it is pertinent that the tadpoles and adults of the anuran

Indexed as

Age FactorsAmphibian ProteinsAnimalsDisease SusceptibilityDNA Virus InfectionsFemaleHost-Pathogen InteractionsInterferonsIntestinesLarvaMaleMyeloid CellsRanavirusViral LoadXenopus laevisAmphibian ProteinsInterferonsamphibianinterferonsintestinemyeloid cellsranavirus

Identifiers

PMID34489981
PMCPMC8418544
OpenAlexW3193462852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.