Evidence map›Paper›PMID 34489959›Full record

ArticleFrontiers in immunology2021

The Spleen as a Target to Characterize Immunomodulatory Effects of Down-Stream Processed

Byron Morales-Lange, Jeleel Opeyemi Agboola, Jon Øvrum Hansen, Leidy Lagos, Ove Øyås, Luis Mercado, Liv Torunn Mydland, Margareth Øverland

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Brewers' Yeast (Aquaculture nutrition · 2025
    Article
  2. Article
  3. Heliyon · 2024
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  4. Article
  5. Cohabitation ofFrontiers in cellular and infection microbiology · 2023
    Article
  6. Article
  7. Article
  8. Immune Modulation Ability of Hepcidin from Teleost Fish.Animals : an open access journal from MDPI · 2022
    Article
  9. Article
  10. Dietary Inclusion of HydrolyzedFrontiers in physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Byron Morales-LangeDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Jeleel Opeyemi AgboolaDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Jon Øvrum HansenDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Leidy LagosDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Ove ØyåsDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Luis MercadoGrupo de Marcadores Inmunológicos en Organismos Acuáticos, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Liv Torunn MydlandDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Margareth ØverlandDepartment of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Norwegian University of Life Sciences · NOPontificia Universidad Católica de Valparaíso · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaculture feeds have changed dramatically from being largely based on fishmeal (FM) towards increased use of plant protein sources, which could impact the fish's immune response. In order to characterize immunomodulatory properties of novel functional ingredients, this study used four diets, one based on FM, a challenging diet with 40% soybean meal (SBM), and two diets containing 40% SBM with 5% of

Indexed as

Animal FeedCandidaAnimalsGene OntologyInterferon-gammaSalmo salarSpleenTranscriptomeTumor Necrosis Factor-alphaInterferon-gammaTumor Necrosis Factor-alphaautolysed yeastELISAinactivated yeastSalmo salarsecondary lymphoid organtranscriptomics

Identifiers

PMID34489959
PMCPMC8417602
OpenAlexW3195562475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.