Evidence map›Paper›PMID 34489953›Full record

ArticleFrontiers in immunology2021

Molecular Characterization and Expression Analysis of Intercellular Adhesion Molecule-1 (ICAM-1) Genes in Rainbow Trout (

Xue Zhai, Wei-Guang Kong, Gao-Feng Cheng, Jia-Feng Cao, Fen Dong, Guang-Kun Han, Yan-Ling Song, Chuan-Jie Qin, Zhen Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xue ZhaiDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Wei-Guang KongState Key Laboratory of Freshwater Ecology and Biotechnology, Center for Fish Biology and Fishery Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Gao-Feng ChengDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Jia-Feng CaoDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Fen DongDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Guang-Kun HanDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Yan-Ling SongDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Chuan-Jie QinDepartment of Life Science, Key Laboratory of Sichuan Province for Conservation and Utilization of Fishes Resources in the Upper Reaches of the Yangtze River, Neijiang Normal University, Neijiang, China.
Zhen XuState Key Laboratory of Freshwater Ecology and Biotechnology, Center for Fish Biology and Fishery Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Huazhong Agricultural University · CNChinese Academy of Sciences · CNInstitute of Hydrobiology · CNNeijiang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intercellular adhesion molecule-1 (ICAM-1), known as CD54, is a transmembrane cell surface glycoprotein that interacts with two integrins (i.e., LFA-1 and Mac-l) important for trans-endothelial migration of leukocytes. The level of ICAM-1 expression is upregulated in response to some inflammatory stimulations, including pathogen infection and proinflammatory cytokines. Yet, to date, our knowledge regarding the functional role of ICAM-1 in teleost fish remains largely unknown. In this study, we cloned and characterized the sequence of ICAM-1 in rainbow trout (

Indexed as

Ciliophora InfectionsFlavobacteriaceae InfectionsOncorhynchus mykissRhabdoviridae InfectionsAnimalsFish DiseasesFish ProteinsFlavobacteriumGene Expression RegulationHymenostomatidaInfectious hematopoietic necrosis virusIntercellular Adhesion Molecule-1Fish ProteinsIntercellular Adhesion Molecule-1Flavobacterium columnare G4Ichthyophthirius multifiliisinfectious hematopoietic necrosis virusintercellular adhesion molecule-1mucosal immune responserainbow trout

Identifiers

PMID34489953
PMCPMC8417878
OpenAlexW3195474140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.