Evidence map›Paper›PMID 34489946›Full record

ReviewFrontiers in immunology2021

Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges.

Ehsan Razeghian, Wanich Suksatan, Heshu Sulaiman Rahman, Dmitry O Bokov, Walid Kamal Abdelbasset, Ali Hassanzadeh, Faroogh Marofi, Mahboubeh Yazdanifar, Mostafa Jarahian

RetractedOpen access · goldAbstract readReviewRetracted Publication
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Mechanism of probiotics in the intervention of colorectal cancer: a review.World journal of microbiology & biotechnology · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. TRAIL-Sensitizing Effects of Flavonoids in Cancer.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Ran GTPase and Its Importance in Cellular Signaling and Malignant Phenotype.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 8 countries.

Ehsan RazeghianHuman Genetics Division, Medical Biotechnology Department, National Institute of Genetics Engineering and Biotechnology (NIGEB), Tehran, Iran.
Wanich SuksatanFaculty of Nursing, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand.
Heshu Sulaiman RahmanDepartment of Physiology, College of Medicine, University of Suleimanyah, Suleimanyah, Iraq.
Dmitry O BokovInstitute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russia.
Walid Kamal AbdelbassetDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.
Ali HassanzadehDepartment of Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Faroogh MarofiImmunology Research Center (IRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Mahboubeh YazdanifarStem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, United States.
Mostafa JarahianToxicology and Chemotherapy Unit (G401), German Cancer Research Center, Heidelberg, Germany.
Chulabhorn Hospital · THFederal Research Centre of Nutrition and Biotechnology · RUGerman Cancer Research Center · DENational Institute of Genetic Engineering and Biotechnology · IRPrince Sattam Bin Abdulaziz University · SAStanford University · USTabriz University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversity of Sulaimani · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune cytokine tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has attracted rapidly evolving attention as a cancer treatment modality because of its competence to selectively eliminate tumor cells without instigating toxicity

Indexed as

TNF-Related Apoptosis-Inducing LigandAnimalsApoptosisHumansImmunotherapyNeoplasmsTNF-Related Apoptosis-Inducing Ligandcombination therapymesenchymal stem/stromal cellsnanoparticlesresistancetumor necrosis factor-related apoptosis-inducing ligand

Identifiers

PMID34489946
PMCPMC8417882
OpenAlexW3193460200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.