Evidence map›Paper›PMID 34489710›Full record

ArticleFrontiers in pharmacology2021

Targeted Propolis-Loaded Poly (Butyl) Cyanoacrylate Nanoparticles: An Alternative Drug Delivery Tool for the Treatment of Cryptococcal Meningitis.

Patcharin Thammasit, Chayada Sitthidet Tharinjaroen, Yingmanee Tragoolpua, Volker Rickerts, Radostina Georgieva, Hans Bäumler, Khajornsak Tragoolpua

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  6. Journal of fungi (Basel, Switzerland) · 2025
    Review
  7. Nanomaterials (Basel, Switzerland) · 2025
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Patcharin ThammasitDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Chayada Sitthidet TharinjaroenDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Yingmanee TragoolpuaDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
Volker RickertsMycotic and Parasitic Agents and Mycobacteria, Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Radostina GeorgievaCharité-Universitätsmedizin Berlin, Institute of Transfusion Medicine, Berlin, Germany.
Hans BäumlerCharité-Universitätsmedizin Berlin, Institute of Transfusion Medicine, Berlin, Germany.
Khajornsak TragoolpuaDivision of Clinical Microbiology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Chiang Mai University · THCharité - Universitätsmedizin Berlin · DERobert Koch Institute · DETrakia University · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we describe a nano-carrier system for propolis that is able to cross an

Indexed as

blood-brain barrierCryptococcus neoformansin vivo modelpoly (n-butyl cyanoacrylate) nanoparticlespropolis

Identifiers

PMID34489710
PMCPMC8417799
OpenAlexW3194949443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.