Evidence map›Paper›PMID 34489703›Full record

ArticleFrontiers in pharmacology2021

Dehydrocorydaline Protects Against Sepsis-Induced Myocardial Injury Through Modulating the TRAF6/NF-κB Pathway.

Yadong Li, Li Zhang, Ping Zhang, Zhiying Hao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Nrf2 mediated signaling axis in sepsis-induced cardiomyopathy: potential Pharmacological receptor.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Recent Advances in Alkaloids fromMolecules (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Yadong LiDepartment of Emergency, Second Hospital of Shanxi Medical University, Taiyuan, China.
Li ZhangDepartment of Hemotology, Renmin Hospital of Wuhan University, Wuhan, China.
Ping ZhangDepartment of Hemotology, Renmin Hospital of Wuhan University, Wuhan, China.
Zhiying HaoDepartment of Pharmacy, Shanxi Cancer Hospital, Taiyuan, China.
Renmin Hospital of Wuhan University · CNSecond Hospital of Shanxi Medical University · CNShanxi Provincial Cancer Hospital · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to investigate the effect and mechanism of dehydrocorydaline (Deh), an alkaloidal component isolated from

Indexed as

dehydrocorydalineinflammationmyocardial injurysepsisTRAF6/NF-κB pathway

Identifiers

PMID34489703
PMCPMC8416759
OpenAlexW3196264813

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.