Evidence map›Paper›PMID 34489701›Full record

ArticleFrontiers in pharmacology2021

Short-and Long-Term Expression of Vegf: A Temporal Regulation of a Key Factor in Diabetic Retinopathy.

Claudio Bucolo, Annalisa Barbieri, Ilaria Viganò, Nicoletta Marchesi, Francesco Bandello, Filippo Drago, Stefano Govoni, Gianpaolo Zerbini, Alessia Pascale

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Claudio BucoloDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Annalisa BarbieriDepartment of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.
Ilaria ViganòComplications of Diabetes Unit, Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
Nicoletta MarchesiDepartment of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.
Francesco BandelloDepartment of Ophthalmology, IRCCS Ospedale San Raffaele, Vita-Salute University, Milan, Italy.
Filippo DragoDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Stefano GovoniDepartment of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.
Gianpaolo ZerbiniComplications of Diabetes Unit, Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
Alessia PascaleDepartment of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.
University of Pavia · ITIRCCS Ospedale San Raffaele · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the role of vascular endothelial growth factor (VEGF) at different phases of diabetic retinopathy (DR), we assessed the retinal protein expression of VEGF-A

Indexed as

akita mousediabetesELAV/HuRhyperglycemiaretinopathyVEGF

Identifiers

PMID34489701
PMCPMC8418071
OpenAlexW3195829597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.