ArticleCommunications biology2021
Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 26 citations in OpenAlex.
- Cardiovascular Organoids With Adjustable Endothelial Composition via SOX17-Engineered hPSCs.Biotechnology and bioengineering · 2026Article
- Human iPSC-derived heart valve-like assembloids model valve development and disease pathology.Cell stem cell · 2026Article
- Differentiation of human induced pluripotent stem cells into cardiac valve cells using 2D and 3D differentiation protocols.Stem cell research & therapy · 2026Article
- Hypergraph representations of single-cell RNA sequencing data for improved cell clustering.Bioinformatics (Oxford, England) · 2026Article
- Engineering aortic valves via transdifferentiating fibroblasts into valvular endothelial cells without using viruses or iPS cells.Bioactive materials · 2025Article
- APOE-NOTCH axis governs elastogenesis during human cardiac valve remodeling.Nature cardiovascular research · 2024Article
- Generation and characterisation of scalable and stable human pluripotent stem cell-derived microvascular-like endothelial cells for cardiac applications.Angiogenesis · 2024Article
- Directed Differentiation of Human Induced Pluripotent Stem Cells to Heart Valve Cells.Circulation · 2024Article
- Article
- Models for calcific aortic valve disease in vivo and in vitro.Cell regeneration (London, England) · 2024Review
- Bibliometrics analysis based on the Web of Science: Current trends and perspective of gastric organoid during 2010-2023.World journal of gastroenterology · 2024Article
- Feeder-free generation and characterization of endocardial and cardiac valve cells from human pluripotent stem cells.iScience · 2024Article
- A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization.Nature communications · 2023Article
- Hypoplastic Left Heart Syndrome: Signaling & Molecular Perspectives, and the Road Ahead.International journal of molecular sciences · 2023Review
- Role and Mechanism of BMP4 in Regenerative Medicine and Tissue Engineering.Annals of biomedical engineering · 2023Review
- Cellular and Molecular Mechanisms Underlying Tricuspid Valve Development and Disease.Journal of clinical medicine · 2023Review
- Identifying molecular and functional similarities and differences between human primary cardiac valve interstitial cells and ventricular fibroblasts.Frontiers in bioengineering and biotechnology · 2023Article
- Endocardium in Hypoplastic Left Heart Syndrome: Implications from In Vitro Study.Journal of cardiovascular development and disease · 2022Article
- Probing single ventricle heart defects with patient-derived induced pluripotent stem cells and emerging technologies.Birth defects research · 2022Review
- Endocardial Regulation of Cardiac Development.Journal of cardiovascular development and disease · 2022Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
The cardiac valvular endothelial cells (VECs) are an ideal cell source that could be used for making the valve organoids. However, few studies have been focused on the derivation of this important cell type. Here we describe a two-step chemically defined xeno-free method for generating VEC-like cells from human pluripotent stem cells (hPSCs). HPSCs were specified to KDR
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.