Evidence map›Paper›PMID 34489458›Full record

ArticleNature communications2021

Growth-coupled selection of synthetic modules to accelerate cell factory development.

Enrico Orsi, Nico J Claassens, Pablo I Nikel, Steffen N Lindner

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Synthetic CmBio · 2025
    Article
  6. Article
  7. Modular pathway engineering for enhanced production ofApplied and environmental microbiology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Leveraging EngineeredACS synthetic biology · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Disentangling the Regulatory Response ofACS synthetic biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Enrico OrsiMax Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany.ORCID 0000-0002-4741-0344
Nico J ClaassensLaboratory of Microbiology, Wageningen University, Wageningen, The Netherlands.ORCID 0000-0003-1593-0377
Pablo I NikelThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-9313-7481
Steffen N LindnerMax Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany. Lindner@mpimp-golm.mpg.de.ORCID 0000-0003-3226-3043

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biological FactorsEscherichia coliHumansMetabolic EngineeringMetabolic Networks and PathwaysRecombinant ProteinsSaccharomycetalesSynthetic BiologyBiological FactorsRecombinant Proteins

Identifiers

PMID34489458
PMCPMC8421431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.