Evidence map›Paper›PMID 34489370›Full record

ArticleJournal of microbiology and biotechnology2021

Codon Optimization, Soluble Expression and Purification of PE_PGRS45 Gene from

Tao Xu, Minying Li, Chutong Wang, Meili Yuan, Xianyou Chang, Zhongqing Qian, Baiqing Li, Meiqun Sun, Hongtao Wang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tao XuDepartment of Clinical Laboratory, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Minying LiAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Chutong WangAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Meili YuanAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Xianyou ChangThe Infectious Disease Hospital of Bengbu City, Bengbu, Anhui 233000, P.R. China.
Zhongqing QianAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Baiqing LiAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Meiqun SunAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Hongtao WangAnhui Province Key Laboratory of Immunology in Chronic Diseases, Anhui Key Laboratory of Infection and Immunity, School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Bengbu Medical College · CNThe Second Affiliated Hospital of Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have demonstrated that PE_PGRS45 is constitutively expressed under various environmental conditions (such as nutrient depletion, hypoxia, and low pH) of the in vitro growth conditions examined, indicating that PE_PGRS45 protein is critical to the basic functions of

Indexed as

CodonGenes, BacterialAnimalsAntibodiesAntibody FormationBase SequenceEscherichia coliImmune SeraMycobacterium tuberculosisRabbitsRecombinant ProteinsSequence AlignmentAntibodiesCodonImmune SeraRecombinant Proteinscodon optimizationMycobacterium tuberculosisPE_PGRS45 proteinpolyclonal antibodyRv2615csoluble expression

Identifiers

PMID34489370
PMCPMC9705950
OpenAlexW3198313110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.